1601006158 case presentation

 LONG CASE 

46y/M came with c/o drowsiness (altered sensorium) since 19/05/2022 morning,
c/o vomiting (3-4 episodes) since 3weeks
Hiccups since 3weeks
Burning micturition present since 1month

HOPI:

Pt was apparently asymptomatic 
3weeks back, then pt developed c/o vomiting ,had 4-5 episodes, containing food particles,non bilious.
Pt c/o deviation of mouth and giddiness since (18/05/2022)
(18/05/2022)- GRBS recorded high value for which he was given NPH 10 IU and HAI 10 IU
No c/o fever/cough/cold
No significant h/o previous UTIs
No c/o chest pains/palpitations/syncopal attacks

Past History:

10yrs back pt had c/o polyuria and was diagnosed with Type 2 DM, started on OHA 10 yr back, 
h/o small injury on leg which gradually progressed to non healing ulcer extending upto below knee eventually ended with below knee amputation 1yr back i/v/o development of wet gangrene
OHAs been converted to Insulin since 2 yrs
Delayed Wound healing present- wound healing took 2 months time to heal
3 years back pt underwent Cataract surgery

K/c/o DM type 2 on medication-insulin

Not a k/c/o HTN/Epilepsy/TB/BA/Thyroid disorder/CAD/CVD
Not on any other medication
No h/o blood transfusion

Personal History:

Married
Appetite-Normal
Diet-Vegetarian
Bowel and Bladder - Regular
Micturition- burning micturition present
Habits/Addiction:
Alcohol- 
Not consuming alcohol since 1 yr.
Previously (1yr back) Regular consumption of alcohol, about 90mL whiskey consumed almost daily.
Also 1 month on & off   consumption pattern previously present

Family history:
Not significant

Vitals @ Admission:
BP: 110/80 mmHg
HR: 98 bpm
RR: 18 cpm
TEMP: 101F
SpO2: 98% on RA
GRBS: 124 mg/dL

General Examination: 

Pallor present
No Icterus/Cyanosis/Clubbing/Koilonychia/Lymphadenopathy/Edema
No dehydration
Thyroid normal

Systemic Examination:

CVS: S1S2 heard, No murmurs
RS: BAE+,NVBS
P/A: Soft, Non tender
CNS: 
Pt is having altered sensorium
Reflexes: (Biceps/Triceps/Knee/Ankle/Plantar)-
Normal

Power: Normal(5/5) in both Upper and Lower limbs
Tone: Normal in both Upper and Lower limbs

No meningeal signs

Clinical Images:


































Provisional Diagnosis:

Right Emphysematous Pyelonephritis with Left Acute Pyelonephritis secondary to Sepsis
H/o Type 2 DM since 10 yrs

Investigations Reports:



XRay- KUB



24/05/2022





Xray KUB:




Xray KUB-


USG Abdomen & Pelvis-





Treatment:
INJ. MEROPENEM 500mg IV BD
INJ. ZOFER 4mg IV TID
INJ. PAN 40mg IV OD
IV Fluids- NS,RL @ 100 mL/hr
BP/HR/RR/SpO2 charting
Temp charting 4th hrly
RT feeds- 2nd hrly 100 mL water


-----------------------------------------------------------------------------------------------------------------------------


SHORT  CASE 

20 year old female student by occupation came with the chief complaints of abdominal pain since a weak 

History of 3 episodes of vomiting present( bilious in content non projectile).

Chief complaints of pain abdomen in epigastric region insidious in onset gradually progressive in nature associated with vomitings.

Patient was apparently asymtomatic 3 years back, met with an RTA and was admitted in hospital and diagnosed with Diabetes type 1 and was on Insulin mixtard subcutaneous ( 12u----x-----12u ).

Patient was alright till 8 months back then she had epigastric pain radiating to back insidious in onset and was diagnosed with acute pancreatitis and was on conservative management till then.

After 10 days, she developed hyperpigmented spots and patches on her lower back and lower limbs for which she consulted the doctor several times but they did not resolve. 

Non alcoholic , Non smoker.


GENERAL EXAMINATION

NO Pallor , Icterus , Cyanosis , Clubbing ,lymphadenopathy.

Vitals 
Temp - afebrile
BP      - 120/100 mm hg 
PR      -  120 bpm. 
RR      - 19 cpm 
spo2  100 @RA 
GRBS  - 259 mg/dl @ 3 Pm
CVS   - S1, S2 heard 
RS     : bae present 
P/A   : soft , tender , Guarding Present
CNS  : NA











INVESTIGATION

On 24/03/2022
Serum Lipase      -  135
Serum Amylase   -  261


On 28/03/2022
Serum Lipase      - 36  
Serum Amylase   - 69


RBS             -  292 mg/dl

Urine Protein/Creatinine Ratio :

Spot urine protein : 45.7 mg/dl

Spot urine creatinine : 83mg/dl

Ratio : 0.55


Sickling Test on 27/03/22 - Negative

Rapid Dengue 27/02/22     - Negative

Serum Lipid Profile on 24/03/2022

Total Cholesterol  -  261
Triglycerides         -   #932
HDL Cholesterol   -  #81
LDL Cholesterol    -  # 150

HAEMOGRAM  23/03/2022
Haemoglobin  -  13 gm/dl
Total Count     -   13,200
RBC                  -  5.46
Platelet Count -  3.36 lakh

HAEMOGRAM 27/03/2022 
Haemoglobin  - 11.7 gm/dl
Total Count     - 8,300
RBC                  - 4.87
Platelet Count - 3.68 lakh

RFT
S Urea            - 29
S Creatinine  - 0.7
Uric acid       -  8.8
S Calcium     -  10.2
Na                  - 137
K                    - 4.5
Cl                   - 98

LFT
Total Bilirubin    - 1.52
Direct Bilirubin   - 0.62
Ast                      - 17
Alt                       - 9
Alk P                   - 181
Total Protein     - 6.8
Albumin             - 3.37
A/G                    - 0.98
 
CRP                   - 

HbA1c   -  6.9 %

Serology          - 


ECG

2D Echo

Chest Xray PA View

USG Abdomen

CECT Abdomen


DIAGNOSIS 

Acute Pancreatitis with DKA with Type 1 Diabetes Mellitus ( since 3 year)


TREATMENT

1. Nbm till further orders.
2. IVF- NS & RL @ 150ml/hr.
3. Inj HAI ( 39ml Normal Saline + 40 IU HAI ) @ 4 ml / hr according to Algorithm
4. Inj. Pantop 40mg/IV/OD.
5. Inj. Zofer 4mg/IV/OD.
6. Inj. Tramadol 1amp in 100 ml/NS/IV/BD.
7. Inj. THIAMINE 2amp in 1 NS/IV/TID.
8. Monitor vitals.
9. Measure abdominal girth




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