1701006040 CASE PRESENTATION

 LONG  CASE 

A 46 year old male came with chief complaints of:

     

        Burning micturition present since 10 days

        Vomiting since 2 days  ( 3 - 4 episode)

        Giddiness and deviation of mouth since 1 day 


HISTORY OF PRESENTING ILLNESS:   

    Patient was apparently asymptomatic 10years back, he complained of polyuria for which he was diagnosed with Type 2 diabetes mellitus he was started on OHAs, 3years back OHAs were converted to insulin.

   20 days back, he developed vomiting , containing food particles and  non bilious. He also complained of deviation of mouth and giddiness 1 day

His  GRBS  was also recorded high , for which he was given NPH 10 IU and HAI 10 IU

No history  of fever/cough/cold
No history of previous UTIs
No history of  chest pains/palpitations/syncopal attacks






PAST HISTORY:
    
      10yrs back patient complained of polyuria and was diagnosed with Type 2 DM and started on OHA( oral hypoglycemic agents).

OHAs were converted to insulin 3 years back

3 years back , he underwent cataract surgery

1 year back, he had h/o small injury on leg which gradually progressed to non healing ulcer extending upto below knee eventually ended with below knee amputation  i/v/o development of wet gangrene

Delayed Wound healing present- wound healing took 2 months time to heal


Not a k/c/o HTN/Epilepsy/TB/BA/Thyroid disorder/CAD/CVD

Not on any other medication

No h/o blood transfusion


PERSONAL HISTORY:

Diet - Mixed

Appetite- normal

Sleep- Adequate 

Bowel and bladder- Regular

Micturition- burning micturition present

Habits/Addiction:

Alcohol- 

Not consuming alcohol since 1 yr.

Previously (1yr back) Regular consumption of alcohol, about 90mL whiskey consumed almost daily.Also 1 month on & off  consumption pattern previously present



FAMILY HISTORY:

Not significant

Vitals @ Admission:
BP: 110/80 mmHg
HR: 98 bpm
RR: 18 cpm
TEMP: 101F
SpO2: 98% on RA
GRBS: 124 mg/dL


GENERAL EXAMINATION:

Pallor present
No Icterus/Cyanosis/Clubbing/Koilonychia/Lymphadenopathy/Edema
No dehydration


















SYSTEMIC EXAMINATION:

CVS: S1S2 heard, No murmurs

RS: BAE+,NVBS

P/A: Soft, Non tender

CNS

Patient is having altered sensorium

Reflexes: (Biceps/Triceps/Knee/Ankle/Plantar)Normal

Power: Normal(5/5) in both Upper and Lower limbs

Tone: Normal in both Upper and Lower limbs

No meningeal signs


INVESTIGATIONS:


On 19/5/22:









X ray KUB


CT scan 



USG 










20.05.22
LDH- 192
24hr Urinary protein- 434
24hrs Urinary creatinine- 0.5






Pus cells






21.5.22
Hemoglobin- 6.8g%
TLC- 22,500cells/cumm
Platelets- 1.4lakhs/cu.mm

Urea- 155mg/dl
Creatinine- 4.7
Uric acid- 7.1
Phosphorus- 2.0
Sodium- 126
Potassium- 2.6
Chloride- 87

22.5.22
Hemoglobin- 7.2
TLC- 17,409
Platelet count- 1.5

Urea- 162
Uric acid- 5.0
Sodium- 125
Chloride- 88

23.5.22

Hemoglobin- 6.7
TLC- 21,000
Platelet count- 1.5

Urea- 160
Uric acid- 7.5
Sodium- 130
Chloride- 97


24.5.22

Hemoglobin- 6.8
TLC- 24000
Platelet count- 1.6


Sodium- 134
Chloride- 98




27.5.22
Hb- 7
TLC- 22,000
Platelet count- 26,000
Urea- 144
Creatinine - 4.8
Uric acid-9.1
Phosphorus- 4.8
Sodium- 135
Potassium- 4.3
Chloride- 98
Fasting blood sugar- 149

29.5.22
Hb- 6.4
TLC- 14,700
Platelet count- 6000
Urea - 149
Creatinine- 4.4
Uric acid- 9.2

30.5.22

Hb- 6.4
TLC- 13,700
Platelet count- 50000
Urea - 146 
Creatinine- 4.2
Uric acid- 9.1

X ray KUB 





PROVISIONAL DIAGNOSIS:

Right emphysematous pyelonephiritis and left acute pyelonephiritis and encephalopathy secondary to sepsis.
H/o of Type 2 Diabetes mellitus since 10years


TREATMENT: 




Day 1 to Day 3:
INJ. MEROPENEM 500mg IV BD
INJ. ZOFER 4mg IV TID
INJ. PAN 40mg IV OD
IV Fluids- NS,RL @ 100 mL/hr
BP/HR/RR/SpO2 charting
Temp charting 4th hrly
RT feeds- 2nd hrly 100 mL water

Day 4
INJ. MEROPENEM 500mg IV BD
INJ. ZOFER 4mg IV TID
INJ. RANTAC 50mg IV OD
INJ. KCl 2 Amp in 500 mL NS over 4.5 hrs infusion
IV Fluids- NS,RL @ 100 mL/hr
SYP. POTCHLOR 10 mL in 1 glass of water TID
SYP. MUCAINE GEL 10 mL PO TID
7 point profile
BP/HR/RR/SpO2 charting
Temp charting 4th hrly
RT feeds- 2nd hrly 100 mL water

Day 5 to Day 10:
INJ. MEROPENEM 500mg IV BD (Day 6)
INJ. ZOFER 4mg IV TID
INJ. RANTAC 50mg IV OD
INJ. LASIX 40 mg IV BD
IV Fluids- NS,RL @ 100 mL/hr
SYP. MUCAINE GEL 10 mL PO TID
GRBS 7 point profile
INJ.HAI SC TID ACC to GRBS
TAB.DOLO 650 mg SOS
BP/HR/RR/SpO2 charting
Temp charting 4th hrly

Day 11:
INJ. COLISTIN 2.25 MU IV OD(Day 4)
INJ. ZOFER 4mg IV TID
INJ. RANTAC 50mg IV OD
INJ. LASIX 40 mg IV BD
IV Fluids- NS,RL @ 100 mL/hr
SYP. MUCAINE GEL 10 mL PO TID
GRBS 7 point profile
INJ.HAI SC TID ACC to GRBS
TAB.DOLO 650 mg SOS

Day 12:
SDP Transfusion done I/v/o low platelet count 
Pre transfusion counts:
Hb:6.2 g/dL
TLC:14700
PLt:6000

Post transfusion counts:
Hb:6.4
TLC:13700
PLt:50000

INJ. COLISTIN 2.25 MU IV OD(Day 5)
INJ. ZOFER 4mg IV TID
INJ. RANTAC 50mg IV OD
INJ. LASIX 40 mg IV BD
IV Fluids- NS,RL @ 100 mL/hr
SYP. MUCAINE GEL 10 mL PO TID
GRBS 7 point profile
INJ.HAI SC TID ACC to GRBS
TAB.DOLO 650 mg SOS


-------------------------------------------------------------------------------------------------------------------------------------------------------------------

SHORT  CASE 

51 year old male patient who is resident of chityal ,and works in a transportation company came to the hospital with complaints of 

 Fever since 10 days

 Cough since 10 days 

 shortness of breath since 6 days 

HISTORY OF PRESENTING ILLNESS:

Patient was apparently asymptomatic 10 days back , then he developed 

Fever since 10 days which is high grade , with chills and rigors , intermittent ,relieving with medication.

Associated with cough and shortness of breath.

Cough since 10 days which is productive ,mucoid in consistency,whitish ,scanty amount ,more during night times and on supine position ,non foulsmelling ,non bloodstained .

Right sided chest pain - diffuse , intermittent ,dragging type , aggravated on cough ,non radiating ,not associated with sweating , palpitations.

Shortness of breath since 6 days , insidious onset , gradually progresive ,of grade 3 - (MMRC scale ),not associated with wheeze ,no orthopnea ,no Paroxysmal nocturnal dyspnea, no pedal edema .

 History of pain abdomen or abdominal distension.

No history of , vomiting ,loose stools .

No history of burning micturition.


PAST HISTORY:

Patient gives history jaundice 15 days back that resolved in a week .

No history of Diabetes , Hypertension , Tuberculosis ,Bronchial asthma ,COPD , coronary artery disease , Cerebrovascular accident ,thyroid disease.

FAMILY HISTORY:

No history of Tuberculosis or similar illness in the family 

PERSONAL HISTORY:

           Patient is a chronic smoker - smokes 5 cigarettes per day from past 25 years .

He is a Chronic alcoholic - cosumes 300 ml whisky per day ,but stopped since 3 months.

No bowel and bladder disturbances


GENERAL EXAMINATION:

Patient is moderately built and nourished.

He is conscious, cooperative,comfortable.

No signs of pallor ,cyanosis ,icterus ,koilonychia , lymphadenopathy ,edema .


Vitals : 

Patient is afebrile .

Pulse - 86 beats / min ,normal voulme ,regular rhythm,normal character ,no radiofemoral delay,radioradial delay.

BP - 110/70 mmhg ,measured in supine position in both arms .

Respiratory rate -22 breaths / min








SYSTEMIC EXAMINATION :

Respiratory system examination:

Inspection:-

Upper respiratory tract - oral cavity- Nicotine staining seen on teeth and gums , nose & oropharynx appears normal. 

Chest appears Bilaterally symmetrical & elliptical in shape

Respiratory movements appear to be decreased on right side and it's Abdominothoracic type. 

Trachea is central in position & Nipples are in 4th Intercoastal space

Apex impulse visible in 5th intercostal space

No signs of volume loss

No dilated veins, scars, sinuses, visible pulsations. 

No rib crowding ,no accessory muscle usage.


Palpation:-

All inspiratory findings are confirmed by palpation.

Spine position is normal and no tenderness seen.

Trachea central in position

Apical impulse in left 5th ICS, 1cm medial to mid clavicular line.

Cricosternal distance is 3finger breadths

Measurements:

     Chest circumference-95cm on expiration 

                                           98 cm on inspiration 

    Chest expansion - 3 cm

     Hemithorax- right- 48cm   left - 46 cm

     Ap diameter-32 cm

     Transverse diameter-26 cm

PERCUSSION:stony dullness is observed( large pleural effusion)


Percussion on right side

Supraclavicular- resonant 

Infraclavicular-resonant 

Mammary-dull

Inframammary-dull

Suprascapular-resonant

Interscapular-dull

Intrascapular-dull

Percussion on left side of above  areas- resonant 


AUSCULTATION:

Auscultation on right side:

Supraclavicular- NVBS 

Infraclavicular-  NVBS 

Mammary-decreased

Inframammary-decreased

Suprascapular-NVBS

Interscapular-decreased

Intrascapular- decreased


Auscultation on left side of above  areas- NVBS (normal vesicular breath sounds)


Other systems examination : 


Gastrointestinal system 

 Inspection - 

Abdomen is distended.

Umbilicus is central in position and slightly retracted and inverted.

All quadrants of abdomen are equally moving with respiration except Right upper quadrant .

No visibe sinuses ,scars , visible pulsations or visible peristalsis


Palpation :

All inspectory findings are confirmed.

No tenderness on palpation.

Liver - is palpable 4 cm below the costal margin and moving with respiration.

Liver span increased(18cm)- normal is 13cm

Spleen : not palpable.

Kidneys - bimanually palpable


Percussion  is normal.


Auscultation- bowel sounds heard .

No bruits and venous hum.


Cardiovascular system - 


S1 and S 2 heard in all areas ,no murmurs

Central nervous system - Normal

Per rectal examination_ Normal


Final Diagnosis : 


1- Right sided Pleural effusion likely infectious etiology. 

2- Hepatomegaly - ? Hepatitis or ? Chronic liver disease 



Investigations : 

X ray findngs-ELLIS curve (s shaped curve/Damoiseaus curve)-curved shadow at the lung base,blunting the costophernic angle and ascending towards the axilla.

Shifting dullness is seen on examination









Pleural fluid analysis : 

Colour - straw coloured 

Total count -2250 cells

Differential count -60% Lymphocyte ,40% Neutrophils 

No malignant cells.

Pleural fluid sugar = 128 mg/dl

Pleural fluid protein / serum protein= 5.1/7 = 0.7 

Pleural fluid LDH / serum LDH = 190/240= 0.6

Interpretation: Exudative pleural effusion.


Other investigations : 

Serology negative 

Serum creatinine-0.8 mg/dl 

Clinical urine tests -Normal 



Liver function tests 



Final Diagnosis : 


1- Right sided Pleural effusion likely infectious etiology. 

2- Hepatomegaly - ? Hepatitis or ? Chronic liver disease 


Treatment 

Inj. PIPTAZ 2.5gm iv QID
Tab. AZITHRO 500 OD
Inj. METROGYL 100mlTID
Tab. DOLO 650mg
Inj. NEOMOL 1gm iv
O2 inhalation
Ivf normal saline
Inj opifeneuron
Temperature chart 4 hrly
Bp,spo2 chart 4hrly
Inj. Amikacin iv BD

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