1701006192 CASE PRESENTATION

LONG  CASE:


A 65 year old male, resident of Bhongiri and a Toddy tree climber by occupation, came to the OPD with chief complaints of:

  • Loss of appetite since one week
  • Swelling of the lower limbs since 4 days
  • Decreased urine output since 4 days.

Daily routine:

Patient is a toddy tree climber, wakes up early in the morning at around 5:30 am and goes for work after having breakfast. He comes back for lunch and again goes back to work. He has stopped working  4 years ago because of backpain.


HISTORY OF PRESENTING ILLNESS:

On Day 1:

Patient was apparently asymptomatic 4 years ago, when he developed knee pains and generalized weakness, for which he went to a local hospital, and was given some medication. The pains occured on and off for about 3 years and most recently patient complained of backache 2 months ago radiating towards the right lower limb,  and hence MRI SPINE was taken, which showed L4 - L5 spondylolisthesis with mild sclerosis, and was advised to take analgesics ( cox-2 inhibitors and paracetamol), Multivitamins and calcitriol.


Presently, patient complains of loss of appetitedecreased urine output and bilateral pedal edema of grade 1 since 4 days.

Patient also complains of 3 episodes of vomitings,  2 days ago which were watery, non- bilious , non- blood stained, non - foul smelling and non projectile.

No h/o fever , abdominal pain, headache

PAST HISTORY:

There were no similar complaints in the past.

Patient is a known case of Hypertension and is on medication for the same 

Patient is not a known case of Diabetes mellitus, Bronchial Asthma, T.B, epilepsy and CAD

FAMILY HISTORY:

Insignificant

PERSONAL HISTORY:

DIET- Mixed

APPETITE- Reduced since one week

BOWEL AND BLADDER MOVEMENTS-

Decreased urine output since 4 days

Patient complains of watery stools since 2 days

SLEEP- Adequate

ADDICTIONS - Patient is an occasional alcohol consumer and smokes 10 beedis per day since 40 years

Stopped 6 months ago

No known allergies

GENERAL EXAMINATION:

Patient was examined in a well lit room, with prior consent and adequate exposure.

He is conscious, coherent and co-operative.

He is well oriented to time, place and person.

He is moderately built and moderately nourished.

Bilateral grade 2 pedal edema was present on Day 1 of admission. Now it has reduced.

No signs of pallor, icterus, clubbing, cyanosis, and lymphadenopathy.



VITALS:

Patient is Afebrile

Respiratory rate: 20cpm

Pulse : 80bpm

Blood pressure: 140/70 mm of Hg.

SpO2 : 96 % 


SYSTEMIC EXAMINATION:

CVS: S1, S2 heard. No raised JVP

No murmurs were heard.

CNS

Conscious 

Speech normal

Cranial nerves : Intact

Motor system: normal

Sensory system :Normal

Reflexes normal

No focal abnormality detected

RESPIRATORY SYSTEM: Bilateral air entry present with normal vesicular breath sounds.

PER ABDOMEN: 


Scaphoid in shape 

Mild tenderness present in right lower lumbar region, otherwise normal and soft

Bowel sounds are present.

INVESTIGATIONS:

On Day 1:

Blood-

Hb: 11.2

TLC: 6700

Platelets: 1.82

RBC: 3.37 million

RBS: 92

Urea : 149 mg/dl

Creatinine: 9.9 mg/dl

Na: 138

Ca: 9.5

Phosphate: 4.9

K: 4.4

Cl: 106

CUE- Normal

ABG:

pH-7.2

HCO3- 10.1

PO2- 84

PCO2- 22.3

SpO2-  94.8

Serum Fe- 79

Serology- Negative

LFT-

TB: 0.99 mg/dl

DB: 0.2 mg/dl

AST: 14 IU/L

ALT: 10 IU/L

ALP: 88 IU/L

Total Protein-5.6 g/dl

Albumin: 3.46 g/dl

ECG:

X-ray : On 11/6/22




On 10/6/22:


Ultrasound Abdomen-

  • Bilateral Grade 1 RPD changes with simple renal cortical cysts (Few cystic lesions located in B/L kidneys, largest being 2.7 * 2cm in upper pole of right kidney and 2.3 *2.2 cm in upper pole of left kidney)
  • Supraumbilical hernia with omentocoele

2D-Echo:

  • Mild diastolic dysfunction
  • Mild Left Ventricular Hypertrophy
  • No systolic dysfunction
  • No Mitral regurgitation
  • No Pulmonary artery Hypertension and pulmonary embolism
  • No Regional wall Motion Abnormalities

PROVISIONAL DIAGNOSIS:

AKI on CKD with polycystic kidney disease.

TREATMENT:

Hemodialysis done on Day 1 

ON DAY 2:

Patient is c/c/c

Pulse - 80 bpm

Bp- 110/70 mm of Hg

RR- 20 cpm

SpO2- 98

Grbs- 96 mg/dl

I/O - 900/ 150 ml

Cvs - S1 S2 heard, no murmurs

Respiratory system- BAE+, NVBS

Cns- NFAD

Per abdomen - soft, non tender

TREATMENT GIVEN:

  • Tab. Lasix 40 mg / PO/ BD
  • Tab. Nodosis 500 mg PO/OD
  • Tab. Pantop 40mg PO/ BD
  • Tab. MVT PO / OD
  • Tab. Shelcal 500 mg PO/ OD
  • BP/ temperature/ pulse rate/ Urine output monitoring every 4th hourly.
  • GRBS every 12th hourly.
  • Salt and fluid restriction.



On Day 3:

Patient is c/c/c

Pulse - 110 bpm

Bp- 100/70 mm of Hg

RR- 19 cpm

SpO2- 98

Grbs- 96 mg/dl

Cvs - S1 S2 heard, no murmurs

Respiratory system- BAE+, NVBS

Cns- NFAD

Per abdomen - soft, non tender.

I/O : 700/350 ml

Blood urea : 129 mg/dl

Sr. Creatinine : 8.4 mg/dl

Na: 138

K: 3.7

Cl: 99


TREATMENT GIVEN:

SECOND ROUND OF HEMODIALYSIS DONE

  • Tab. Lasix 40 mg / PO/ BD
  • Tab. Nodosis 500 mg PO/OD
  • Tab. Pantop 40mg PO/ BD
  • Tab. MVT PO / OD
  • Tab. Shelcal 500 mg PO/ OD
  • BP/ temperature/ pulse rate/ Urine output monitoring every 4th hourly.
  • GRBS every 12th hourly.
  • Salt and fluid restriction.


On Day 4:

Patient is c/c/c

Pulse - 92 bpm

Bp- 110/70 mm of Hg

RR- 18 cpm

SpO2- 98

Grbs- 97 mg/dl

Cvs - S1 S2 heard, no murmurs

Respiratory system- BAE+, NVBS

Cns- NFAD

Per abdomen - soft, non tender.


TREATMENT GIVEN:

IV FLUIDS- NS @UO + 30ml/hr

Tab. Lasix 40 mg / PO/ BD

Tab. Nodosis 500 mg PO/OD

Tab. Pantop 40mg PO/ BD

Tab. MVT PO / OD

Tab. Shelcal 500 mg PO/ OD

BP/ temperature/ pulse rate/ Urine output monitoring every 4th hourly.

GRBS every 12th hourly

Salt and fluid restriction.


----------------------------------------------------------------------------------------------------------------

SHORT CASE: 

A 55 yr old female who is house maid by occupation came with chief complaints of

  • Head ache since 20 days
  • Fever since 5 days
  • Neck stiffness since 5 days

HISTORY OF PRESENTING ILLNESS:

     Patient was apparently asymptomatic 20 days back then she developed headache which was insidious onset, gradually progressive, not relieved on medications ,the headache aggravated 5 days back In spite of taking medication. No aggravating factors

Fever which was insidious onset since,intermittent,not relieved on medication.Not associated with chills / rigors,associated with neck stiffness 

One episode of vomiting food particles 3 days ago,non projectile, non bilious, , non blood stained.

No h/o of cold and cough 

No h/o of loose stools 

No h/o of abdominal pain

No h/o of breathlessness, PND , orthopnoea

No h/o of burning micturition, increased frequency of micturition. 


PAST HISTORY:

No history of similar complaints in the past.

7 yrs back she gave history of CVA due to which both upper and lower limbs were paralysed,she took allopathy medicine for 6 months and recovered.

Denovo detected diabetes

Not a known case of Hypertension, Asthma, Epilepsy,

Hysterectomy done at 25 yrs of age.

PERSONAL HISTORY:

Diet: Mixed

Appetite: Normal

Sleep: Adequate 

Bowel and bladder: Regular 

No addictions 

No known allergies

FAMILY HISTORY: Insignificant 

GENERAL EXAMINATION:

The patient was examined in a well lit room, with prior informed consent.

Patient is conscious, coherent, cooperative and is moderately built and malnourished 

No signs of Pallor , Icterus ,Cyanosis ,Clubbing , Lymphadenopathy and  Edema

VITALS :

Afebrile

Pulse rate : 75 bpm

Respiratory rate : 15 cpm 

Blood pressure : 120/70 mm of Hg 

SYSTEMIC EXAMINATION:

CNS EXAMINATION:

Higher mental functions:

-Patient is conscious, oriented to time and place 

-Memory is intact

-Speech and language normal

 

Cranial nerve examination : 

2 nd cranial nerve : Visual acuity - counting fingers from 6m distance 

3,4,6 cranial nerves : extraocular movements present, direct indirect reflexes present. 

5 th cranial nerve : sensations over face present 

7 th cranial nerve : forehead wrinkling present, able to blow cheek, able to open and close eyes, Naso labial folds normal 

8 th cranial nerve : hearing normal, no Nystagmus. 

9, 10 th cranial nerve : uvula centrally placed and symmetrical. 

11 th cranial nerve : trapezius and sternocleidomastoid normal 

12 th cranial nerve : tongue no deviation.

Motor examination:

                                                    

1.Bulk  

Inspection and palpation normal  

     Right Left 

   - MUAC 28 cm 27.5cm 

   - mid forearm 20 cm 20 cm

   - mid thigh 29 cm 30 cm

   - mid calf 25 cm 25 cm 

     

2. Tone 

 - upper limb normal normal 

 - Lower limb normal normal 


3.Power 

- upper limb 5/5 5/5 

- Lower limb 5/5 5/5     


4.Reflexes

 - knee jerk + +

 - Ankle jerk + +

 - Biceps + + 

 - triceps + +

 - Plantar - normal 








Meningeal signs:

1. Nuchal rigidity : present 

2. Kernig sign : positive 

3. Brudzinski sign : positive  


Sensory examination:Normal

Cerebellar examination : Normal


RESPIRATORY EXAMINATION:

Bilateral air entry present 

Normal vesicular breath sounds heard 


CVS EXAMINATION:

S1 and S2 heard 

No murmurs 


ABDOMINAL EXAMINATION:

Soft, non tender abdomen 

No organomegaly 

INVESTIGATIONS:

Hemogram 

Dengue NS1 antigen


CSF analysis : 


Glucose  : 81

Protein : 12.6


Arterial blood gas analysis : 

PH : 7.4

PCo2 : 29.1

PO2 : 88.4

HCO3 : 18

Fasting blood sugar - 168 mg/dl  

Complete urine examination : 

Albumin : positive 

Sugar : nil 

Pus cells : 6-8

Epithelial cells : 3-4

RBC and casts : nil 

RFT:

AST : 69 IU/L

ALT : 68 IU/L

ALP : 135 IU/L

Total protein : 6.4 gm/dl

Albumin : 4.0 gm/dl

Urea : 38 mg/dl

Creatinine : 1.0 mg/dl

Uric acid : 4.9 mg /dl


Serology : Non reactive 

X- ray neck:



MRI - FLAIR: Enhancements seen in leptomeninges and sulcal spaces in bilateral parietal and occipital areas, most likey meningitis.


PROVISIONAL DIAGNOSIS: 

Dengue fever with meningoencephalitis 


TREATMENT 

9 th and 10 th June 2022 :      

Injection ceftriaxone 2 gm / ml BD 

Injection dexamethasone 6 mg intravenous TID

Injection vancomycin 1 gm intravenous sos

Injection paracetamol 1 gm intravenous TID

Tab ecosporin 7 mg per oral OD 

Tab cremaffin 30 peroral 


INVESTIGATIONS ON DAY 2:

Hemogram : 

Hb- 13.1

Tlc-16,400 /mm3 

Neutrophils- 82

Leukocytes -9

Eosinophil -1

Monocyte -8

Platelet count -1.81lakh/mm3 


Arterial blood gas analysis : 

PH - 7.44

PCO2 - 28 

PO2 - 49.3

HCO3-18.7

O2 sat - 85.1

TREATMENT : 

Intravenous fluids NS and RL 

Injection ceftriaxone 2 gm / ml BD 

Injection dexamethasone 6 mg intravenous TID

Injection vancomycin 1 gm intravenous sos

Injection paracetamol 1 gm intravenous SOS

Tab paracetamol 650 mg TID

Tab ecosporin 7 mg per oral OD 

Tab cremaffin 30 peroral 

Tab metformin 500 mg per oral 



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