1801006009 CASE PRESENTATION

long case

CHIEF COMPLAINTS: 

Patient Came to Casualty with chief Complaints of difficulty in breathing since 10 Days

Complaints of swelling of upper limbs and lower limbs since 6 days

Decreased urine output since 6 days

HOPI:



Patient was apparently asymptomatic 1 year back Then he had difficulty in breathing which is Intermittent type, he went to hospital where he was diagnosed with CKD.
He was using a nebulizer to control his SOB on recommendation of a RMP.

10 days back he had sudden onset of difficulty of Breathing, which had progressed to GRADE IV  (unable to walk to bathroom), Orthopnea present, unable to sleep and wakes up gasping for air. ( PND  present).
Edema of both upper and lower limbs
Lower limb Edema which is pitting type upto Thigh 

There is a History of fall from a tree 3 years ago. There was no loss of consciousness on fall. He was admitted to the hospital and developed low backache and neck pain later.
 He had fever, cough, loss of appetite for 2 months, later was diagnosed with Tuberculosis and Diabetes. ATT for 6 months and on Oral Hypoglycemic since then

Seasonal Difficulty in breathing (SOB), On and Off and with diagnosis of CKD 1 year ago. Increased SOB and Edema since 10 days.

DAILY ROUTINE : 

He is a Farmer By Occupation
He wakes Up at 7 pm everyday, Does his morning Routine and has Tea.
Has Breakfast at 8am
Eats Idli or rice for breakfast
Goes to Field for work and returns in the afternoon.
Has Lunch at 2pm, 
He eats Rice and Curry/Non veg for lunch( Has Non veg weekly once).
He sleeps for 2 hours in the afternoon and wakes up at 4pm. 
Watches TV and reads Newspaper and goes for a Walk in the evening.
By 8:30 he has his dinner.
He Eats Rice and Curry for Dinner.
Goes to Sleep by 9pm

After his fall from the tree and injury to his lower back he Stopped going to work since last 3 years and started getting intermittent SOB.
He developed decreased appetite and difficulty in sleeping.

























PAST HISTORY: 

Known Case of Tuberculosis 
Diagnosed 3 years Back and was given Anti-Tubercular Therapy

Known Case of Diabetes II Since Last 3 Years - On Oral Hypoglycemic Drugs.

Known Case Of Chronic Kidney Disease.

Diagnosed with Hypertension When he came to the Hospital. No prior use of Anti hypertensive Drugs.
No H/o Asthma, Epilepsy.

PERSONAL HISTORY : 

Diet - Mixed
Appetite - Decreased
Sleep - Inadequate (PND)
Bowel - Regular
Bladder - Decreased Urinary Output
Addictions - Alcohol use since 30 years. Stopped Drinking 3 months ago.
Smokes Beedi. Stopped 3 months ago.
No allergies

TREATMENT HISTORY
Metformin - For Diabetes
Use of Anti tubercular Drugs in the past.


GENERAL EXAMINATION

Patient was conscious coherent and cooperative.
Moderately Built and Well Nourished

No signs of pallor, icterus, clubbing, generalized lymphadenopathy.

Pedal Edema - Bilateral, Pitting type

VITALS
Temperature - Afebrile
Pulse Rate - 102 bpm
Respiratory Rate - 15cpm
Blood Pressure - 150/90mmg
Sp02 - 97% at Room air
GRBS - 203 mg/dl

SYSTEMIC EXAMINATION: 

CVS EXAMINATION

INSPECTION
No Palpitations

JVP mild raise

PALPATION

Apex Beat - Diffuse Apex Beat on left lateral position.
No parasternal Heave
No palpable P2

Pulse - Regular 

Auscultation : 
S1 S2 Heard


RESPIRATORY SYSTEM



Bilateral Air entry Present
Breathing from Mouth.
Trachea - Midline
Chest is bilaterally symmetrical and elliptical 
Supraclavicular Hollowing Present

Percussion                    Right                   Left
Supra clavicular:        resonant            resonant   
Infra clavicular:          resonant            resonant 
Mammary:                  dull                   resonant
Axillary:                      dull                   resonant 
Infra axillary:             dull                   resonant
Supra scapular:         resonant            resonant
Infra scapular:           dull                    resonant 
Inter scapular:           dull                    resonant     


Auscultation:              Right.                   Left

Supra clavicular:.       NVBS                NVBS
Infra clavicular:          NVBS                NVBS
Mammary:                 decreased           NVBS
Axillary:                     decreased           NVBS
Infra axillary:             decreased           NVBS
Supra scapular:          NVBS                NVBS
Infra scapular:           decreased            NVBS
Inter scapular:           decreased            NVBS


Central Nervous System
Higher Motor Functions Normal

PER ABDOMEN

INSPECTION 
Abdomen is Mildly distended
Umbilicus is central in position
A visible scar due to injury due to a fall around the umbilicus.

PALPATION -
No Tenderness on superficial palapation.
Temperature - Afebrile

Liver is Non Tender

Spleen is Not palpable

Percussion -
Fluid thrill and 
Auscultation - Bowel Sounds Heard

INVESTIGATIONS : 

X- RAY 






ECG 


2D ECHOCARDIOGRAPHY

Aortic Valve - Sclerotic

Moderate MR +, Moderate TR+ with PAH : Trivial Eccentric TR+

Global Hypokinetic , No AS/MS

Moderate LV Dysfunction+

Diastolic Dysfunction present



ULTRASOUND

USG CHEST

Free fluid noted in bilateral pleural spaces (Right more than Left) with underlying collapse 

USG ABDOMEN and PELVIS

Mild to Moderate Ascites
Raised Echogenicity of Bilateral Kidneys

LIVER FUNCTION TEST

Total Bilirubin - 0.9 mg/dl
Direct Bilirubin - 0.1 mg/dl
Indirect Bilirubin - 0.8 mg/dl

Alkaline Phosphatase - 221 u/l
AST - 40 u/l
ALT - 81 u/l

Protein Total - 6.8g/dl
Albumin - 4.2 g/dl
Globulin - 2.6 g/dl
Albumin:Globulin Ratio - 1.6

Renal Function Test

Urea - 64 
Creatinine - 4.3
Na+   - 138
K+      - 3.4
Cl-       - 104

Spot urine Protein - 34
Spot urine creatinine - 14.8

Spot Urine : Creatinine Ratio - 2.29


Fasting Blood Sugar - 93mg/dl
PLBS - 152 mg/dl

HbA1c  - 6.5%

ABG :
pH : 7.3
pCO2 - 28.0
pO2 - 77.4
HCO3-. - 13.5
Sat O2 - 94.7

PROVISIONAL DIAGNOSIS

Heart Failure with M Secondary to Renal Failure,
With Alcoholic Hepatitis 
Known Case of Diabetes Mellitus II Since 3 Years.
With Bilateral Pleural Effusion

TREATMENT

1)Fluid Restriction less than 1.5 Lit/day

2) Salt restriction less than 1.2gm/day

3) INJ. Lasix 40mg IV / BD

4) TAB MET XL 25 mg 

5) TAB. CINOD 5 MG PO/OD(IF SBP MORE THAN 110 MM HG)

6. INJ. HUMAN ACTRAPID INSULIN SC/TID (ACCORDING TO SLIDING SCALE)

7. INJ. PAN 40 MG IV/OD

8. INJ. ZOFER 4 MG IV/SOS

9. Strict I/O Charting

10. Vitals Monitoring 

11. TAB. ECOSPRIN AV 75/10 MG PO/HS

------------------------------------------------------------------------------------------------
short case

CHIEF COMPLAINTS


A 32 year old male patient presented with complaints of swelling of face, difficulty in swallowing and change in voice in February.


HISTORY OF PRESENTING ILLNESS 


Patient was apparently asymptomatic 16 years back, then in 2007 after exposure to cement dust he developed sudden difficulty in breathing, inability to speak, swelling of face , lips, hands and legs. Emergency tracheostomy was done and treated conservatively following which the symptoms were relieved. 

He was found to be allergic to smoke inhalation of burnt plastic, garbage, any offensive smell, strawdust and cotton.  

He is also allergic to foods like Brinjal, mutton, fish and papaya. 

The symptoms aggravated even on anxiety. Swelling of face increases after any H/O trauma.


Patient used to develop symptoms on and off from the past 16 years. Patient was referred to Outside hospital i/v/o immunotherapy in 2011 and was treated with some unknown medication and was advised precautionary measures against allergens. 


Again in 2016, patient was presented with some complaints as in 2007 when emergency tracheostomy was done, patient since then complains of occasional swelling of face, hand and legs which relieved on taking medication. 


In 2021, Patient presented with complaints of swelling of face and difficulty in breathing and was treated with FFP’s, adrenaline, nebulization, hydrocortisone and symptoms got relieved. Patient had around 6-7 hospital admissions in the past 16 years.


Done in 2020 December 

C4 complement serum is less than 8 mg/dl

C1 esterase inhibitor protein is 65 mg/dl



PAST HISTORY 


Not a k/c/o HTN, DM, CAD, thyroid disorders, epilepsy, TB

PERSONAL HISTORY 


Diet is mixed 

Appetite is normal

Sleep is adequate

Bowel and bladder movements are regular 

No addictions 

He is allergic to straw dust,burnt leaves, garbage, plastic smoke,

He is also allergic to foods like Brinjal, mutton, fish and papaya. 



FAMILY HISTORY


No significant family history



GENERAL EXAMINATION 


Patient is concious coherent and cooperative 

Perioral/lip edema present

Facial puffiness present 


Previous tracheostomy scar present on the neck





Vitals:


Temperature 98.6F

Pulse rate 106bpm

Respiratory rate 18per min

BP 110/70 mmhg 

Spo2 98 at room air 

GRBS 110mg/dl



SYSTEMIC EXAMINATION 


CVS 

s1s2 heard 

No murmurs


RS

Bilateral air entry present

Normal vesicular breath sounds


ABDOMEN

Soft, non tender 

No organomegaly

Bowel sounds heard 


CNS 

Power normal in bilateral upper and lower limbs 

Tone normal in bilateral upper and lower limbs 

Reflexes are normal 

No meningeal signs 

Pupils are reactive bilaterally 



PROVISIONAL DIAGNOSIS 


Angioedema 




TREATMENT


Following treatment was given during the patient’s hospital stay last month:

Inj hydrocortisone 100mg IV stat

Nebulization with adrenaline 1amp stat

Nebulization with budecort tid 

Nebulization with duolin qid 


Patient currently does not use any medication 

Patient used Tab Cetrizine and Prednisone on experiencing similar symptoms


INVESTIGATIONS


These investigations were done during the hospital stay last month 







CBP
Hb – 11.8
TLC – 16600
Neu – 90
Lymp – 06
PCV – 40.5
RDW – 18.2
RBC – 6.3
PLC – 5.3
BT – 2 min 30 sec
CT – 4 min 30 sec
APTT – 35 sec
PT – 18
INR – 1.33

CUE
Alb – trace
Pus cells -2- 3

RBS – 124
B.Urea – 32
S.Creat – 1.2

S.electrolytes
Na+ - 141
K+ - 3.9
Cl- - 105
Ca2+ - 1.11

LFT
TB – 0.89
DB – 0.20
AST- 21
Alt -16
ALP-124
T Protein – 7.3
Albumin -4.59

A/G -1.69

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