1801006036 CASE PRESENTATION

LONG CASE 


A 14 year old female , resident of nagarjun sagar came to opd with a cheif complaint  of pain in both the lower limb and lower back pain since 3 days


HISTORY OF PRESENT ILLNESS 

She is second born child of parents married of 3rd degree consanguinity in 2009. All trimesters were uneventful. She was delivered through Caeserean section because of delayed labour pain with birth weight of 3kg.

Immusnized till date.

2012

She was asymmtomatic upto age of 3 years, then she developed high grade fever with cough and vomittings. She was diagnosed with Sickle cell anaemia. Sickling test positive and Electrophoresis showed HbS. Blood transfusion were given 1packet.

2013

She developed high grade fever, dry cough and cold. She was diagnosed with Bronchopneumonia. X-ray lower lobe consolidation.

2015

She had recurrent episodes of fever, cough , cold i.e Recurrent Bronchopneumonia- 6 episodes in 3years. Urine culture showed Klebsiella growth.

Blood transfusion till date 4 times.

2016

She developed fever, pain abdomen , myalgia and arthralgia. She improved on medications and thus was discharged.

2019

She came with stomach pain and vomittings. She was diagnosed to have Acute pancreatitis.

2023

She was apparently asymptomatic  3 days back then she developed pain in left ankle for which she took TAB.ULTRACET  and since 1 day she developed pain in both knee and after 1 hr she developed tenderness in the calf muscles it is of throbbing type in nature 

No H/o of swelling 

All the peripheral pulses are palpable

No h/o chest pain,shortness of breath,headache and palpitations 

No h/o aphasia or dysphagia, seizures,Severe headache,altered mental status

No

PAST HISTORY 

she is a known case of sickle cell anemia
 H/o of bronchopnemonia
 H/o of  8 PICU admissions 
 H/o of blood transfusion (20 times till now) last transfusion was done in jan 2023
No H/O of asthama,thyroid,Tuberculosis, Hypertension, Diabetes,Epilepsy
No h/o of bone pain with localized swelling 

PERSONAL HISTORY 

Diet-mixed
Appetite-normal
Sleep-adequate
Bowel and bladder movements are regular
No allergies
No addictions 
No h/o of any surgery

FAMILY HISTORY 

3rd degree consanguity of parents

No known affected relatives

IMMUNIZATION HISTORY 

patient is vaccinated according to national immunization schedule
Pneumocccal,typhoid,hepatitis vaccine taken on 23/1/22



GENERAL EXAMINATION 

Patient was conscious, coherent and cooperative. Well oriented to time, place and person.

Pallor present

Icterus absent

Cyanosis, clubbing, lymphadenopathy, Pedal edema absent

Clinical images








Vitals

Temp: Afebrile 

PR- 96 bpm  

RR- 18/Min

Bp-110/70mm of hg

Spo2-99%

BP- 110/70 mmHg

Height-144cm

Weight-36kg

SYSTAMIC EXAMINATION 

CVS-s1 and s2 heard ,no murmurs 

RS-bilateral air entry present,normal         vesicular breath sounds are heard

CNS-no neurological deficit 
 P/A-soft and non tender

PROVISIONAL DIAGNOSIS 
Sickle cell anemia with vaso occlusion crisis

INVESTIGATIONS 

Hemoglobin-8gm/dl
TLC-22,900
PCV-23.1(normal-36 to 46)
BLOOD group -O positive 
Total bilirubin-20.15
Direct bilirubin-14.13
SGOT-170
SGPT-180
ALP-560
CRP-negative
Serology -negative
LDH-
blood urea-20mg/dl

Creatinine-0.4
Electrtrolytes-sodiun- 136 mEq/l
                           Pottasium-4.5 mEq/l
                          Chloride-101mEq/l
                           Calcium 1.02mmol/l

Peripheral smear-
  Anisopoikilocytosis with predominant Sickle cell,normocytes,few microcytes


WBC count increased
PLATELET count increased
 
X-RAY 





TREATMENT-
IVF NS and DNS
Inj PAN 40 mg/day
Inj OPTINUERON
inj DICLO

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SHORT CASE

A 47 year old female .  Homemaker        by occupation. resident of    nalgonda.came to the opd with a cheif complaint of pedal edema since 15day
Shortness of breath since 15 days
cough since13 days
fever since 3 days
History of presenting illness 
patient was apparently asymptomatic
15 days back she developed pedal edema which was insidious in onset initially edema is seen till ankle which is pitting type and Then gradually progressed to knee .
15 days back then she developed SOB which was insidious onset  a from last 12 days(grade 2 to grade  3 sob) and relived on rest for which she went to hospital and her hemoglobin levels found 3% and was advised for blood transfusion .since 4 days sob has reduced to grade 2
she developed cough since 12 days which productive in nature, yellowish white sputum no blood stain,non foul smelling
fever since 3days  associated with chills and rigor
no history of weigh loss
no history of malaise 
she noticed left side facial puffyness after 2 hr it reduced spontaneously
no abdominal distention
 NoPalpitations 
No Paresthesia in hand
No Loss of taste
Past History 
from last 1 year there is pedal edema which is on and off
no history of diabetes, asthama,Hypertension, TB,thyroid and Epilepsy 
Menstrual History 
she attained menarchy at the age of   
earlier she used to have regular 30 days Menstrual cycle with 3 days flow ,no clots

from 22march,2022 she is having regular 20 days cycle ,heavy Menstrual bleeding for 5 days for which she went to hospital and was diagnosed by fibroid uterus and was advised for hysterotomy because of her low hb level surgery was not done.she under went blood transfusion later her Hb was found to be 8gm% which was not adequate for surgery
Since  last 6 months spotting is seen for every 15 to 20 days of cycle
Personal history 
Normal appatite 
Mixed diet
Adequate sleep
Regular Bowel and Bladder movement 
No addictions 
No allergies 
Daily routine-she wake up at 5 am does daily  work(sweeping,washing cloths)then she will have a glass of milk  at 12 pm she will have rice ,dal and curry then she will have sleep for a hour 
Watch TV for 1 to 2 hr then at 9pm she will have dinner(chapati and curry)
Sleep at 10 pm
diet history 
1 glass milk-129 cal,8g
Lunch-rice 2 cups-414 cal,6.6g
            Curry 1 cup -80cal,6g
             Dal 1 cup -89cal,7g
Milk 1 glass -129 cal,6.6 g
Dinner-chapatti2 and half-172 cal,8g
             Curry-80 cal,6
Total -59.6 g and 1091 cal
She is deficit of 1509 cal
Family history 
No History of similar complaints in the family 
Treatment history 
Medroxy progesterone  acetate-once daily for 2 month


Dexorange from last 4 days
General examination 
Patient was consious, coherrent and co-operative. Well oriented with time place and person. Well built and nourished 
Pallor 
B/L pedal edema
No icterus 
No clubbing
No cynosis
No generalized lymphadenopathy 
Vitals
Pulse-114
BP 120/70
Respiratory rate-19cpm
Spo2-96%
Temp-afebrile 
Jvp raised

Systamic examination 

Jvp raised
Parasternal heave
S1 and s2 heard No murmurs 

Rs-  Trachea central
Normal vesicular breath sounds heard 
Right infrascapular wheez
Per abdomen-

INSPECTION: abdomen :round 
Moves with respiration
No abdominal distension 
Umblicus is central and inverted 
No engorged veins
No scars and no sinsus are seen
Hernias orifices are clear.

PALPATION:
All inspectory findings are confirmed 
No tenderness in the abdomen

 PERCUSSION:No significant fingings

AUSCULTATION: Bowel sounds heard 
No bruits.


Cns-no focal neurological deficit 

CILNICAL IMAGES


















Provisional diagnosis-dimorphic anemia with right heart failure

Investigations 








Treatment 
PRBC transfusion 
Inj LASIX 40 mg iv BD


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