1801006037 CASE PRESENTATION

 LONG CASE 


60 YRS OLD MALE WITH THE COMPLAINTS OF UPPER AND LOWER LIMB SWELLING SINCE 10 DAYS

Chief complaints:

A 60 year old gentleman came to the casualty with the cheif complaints of edema of both upper and lower limbs since 10 days,complaints of facial swelling decreased urine output since yesterday, vomiting of 6 episodes on  Saturday , loose stools of 4 episodes  on Sunday 
 Hopi: Patient was apparently asymptomatic 10 days back then he developed Bilateral pedal edema since 10 days which was insidious in onset and gradually progressive in nature  for which he admitted in government hospital. Condition worsened and swelling of face bilateral upper limb started 4 days back .
Complaints of decreased urine output on day before presentation 
Associated with 6 episodes of vomiting food particles as content non bilious non projectile non blood tinged
4 episodes of loose stools watery non blood stained
No history of fever, palpitations, sob, pain abdomen, sweating, burning micturition. 
SEQUENCE OF EVENTS;18 Yrs back he was diagnosed with type2 DM                                                     ↓
Around 6 years back, one fine day when he went to pass urine, patient suddenly had LOC for around 10 mins with involuantry movements of ?Rt Upper limb and lower limb, uprolling of eyes + , tongue bite + frothing from mouth + and he was taken to local hospital where they were said to have to significant findings in CT and he hasn't been started on any medications and sent to home with in 2-3 days.                                                                  ↓
2yrs back patient developed altered sensorium and was having hyperglycemia at private hsptl then he was diagnosed to have DKA and treated with inslin.                                  ↓
4 months back he complained of pedal edema for which they went to nalgonda hsptl and stayed approximately 1 week and resolved edema ,while planning for discharge he suddenly developed vomitings for 3days (non bilious, non projectile vomitings) later on his sensorium deteriorated and aphasia also developed and brought to our hsptl and found out to be having hyponatremia and hypokalemia and corrected with 3%NS and later with in 1-2 days patient became normal and thought of SIADH secondary to ?frontal lobe contusion and he was discharged with normal electrolyts.                                 ↓
10 days back (6/3/23) patient developed pedal edema for which he went nalgonda hsptl again and treated there for 4days and on 10/3/23 he suddenly started having vomitings(6 episodes of vomitings in 2 days) and loose motions (7 episodes in 2 days) later on his sensorium deteriorated and brought to our hsptl on sunday night(12/3/23).


Past history:

History of similar complaints in the past and admitted in the hospital on 23rd December 2022 and discharged on 31 December 2022. There was history of altered sensorium present at the time of previous hospitalisation.


Known case of diabetes from 18 years. On Tab. Glimipride 1mg before breakfast and Tab. Metformin 500 mg after breakfast.


Known case of hypertension since 4 years. On Tab. Telma H(TELMISARTAN 40 mg+ hydrochlorthiazide 12.5mg) in morning and Tab. Cilacar 10mg at night.


Not a known case of tuberculosis, bronchial asthma, CAD, CVD.


PERSONAL HISTORY:


Farmer by occupation. Stopped since 4 years


Appetite decreased from 10 days


Decreased urine output since yesterday


Known alcoholic. Stopped from 20years


Known smoker stopped since 20 years


DAILY ROUTINE OF PATIENT:used to wake up at 6 am and will do his morning rituals by 7:30 am 

and will have breakfast by 8 amwhich consists of rice,curry and goes to work he used to do ctting trees and woods also sometimes he goes to his own feileds where he waters the fields and removes the weeds sowing fertilisers and some cattle rearing too and will have his lunch by 1 pm which consists of rice ,curry and comes to the home by 5 or 6 pm and will freshens up and will have dinner by 8pm and goes to bed by 10pm.



GENERAL PHYSICAL EXAMINATION:

Patient is conscious coherent and cooperative well oriented to time place person

Moderately built and moderately nourished.

No signs of pallor, icterus, cyanosis, clubbing, generalised lymphadenopathy

https://drive.google.com/uc?export=view&id=16VF5Agnb39U2G0IqzARS9DTM3ToulCZg
bilateral pedal edema + 
https://drive.google.com/uc?export=view&id=1RC3KNLQWsflNqTkXbAWzWCNBp2sM95ip
VITALS:

TEMPERATURE: 97.4°F

PULSE RATE: 90bpmRESPIRATORY RATE: 18cpmBLOOD PRESSURE: 140/80mm Hg

SPO2: 97% @ Room air

GRBS:306mg/dl


SYSTEMIC EXAMINATION:



CARDIOVASCULAR SYSTEM:

Inspection : 

Shape of chest- elliptical shaped chest

No engorged veins, scars, visible pulsations

No raised JVP. 

Palpation : Apex beat can be palpable in 5th inter costal space medial to mid clavicular line.No thrills and parasternal heaves can be felt

Auscultation : S1,S2 are heard ,no murmurs.


RESPIRATORY SYSTEM:

Inspection: Shape of the chest : elliptical ,B/L symmetrical , 

Both sides moving equally with respiration 

No scars, sinuses, engorged veins, pulsations

Palpation:Trachea - central

Expansion of chest is symmetrical.

Auscultation:

B/L air entry present . Normal vesicular breath sounds.


CENTRAL NERVOUS SYSTEM: 

Conscious, oriented to time place and person.

GCS on the day of admission was E4 V5 M6

speech : normal

Behavior : normal 

Memory : Imediate memory is slightly impaired recent and remote memory is intact.

No hallucinations or delusions

CRANIAL NERVE EXAMINATION:

1st : Normal

2nd : normal

3rd,4th,6th : normal

5th : sensory intact

7th :no abnormality noted

8th : No abnormality noted.

9th,10th : palatal movements present and equal.

11th,12th : normal.


MOTOR SYSTEM EXAMINATION 

Bulk of the muscle: normal

Tone of muscle : normal

POWER -               


                                    RT. LT

Upper limb               3/5. 3/5

Lower limb               4/5. 4/5


SUPERFICIAL REFLEXES : 

corneal ,conjunctival ,plantar reflexes are present

DEEP TENDON REFLEXES :

BP TRI SUP KNEE ANK PLAN


RT                  ++ + + ++ ++ ++ Flex

LT                   ++ ++ ++ ++ ++ Flex


SENSORY SYSTEM EXAMINATION 

SPINOTHALAMIC SENSATION 

Crude touch normal

Pain normal 

DORSAL COLUMN SENSATION

Fine touch normal

Proprioception normal

CORTICAL SENSATION 

Two point discrimination able to discriminate 

Tactile localization able to localize

CEREBELLAR SIGNS : no

Meningeal signs: no


PER ABDOMEN: soft non tender. 

Inspection:on inspection abdomen is flat, symetrical,and not distended.umbilcus is centre and inverted.no scars,engorged veins are seen.All 9 regions of abdomen are equally moving with respiration.all hernial orfices are clear.

Palpation:on palpation abdomen is soft , no tenderness no other palpable organs are felt.On bimanual examination of kidney is not palpable.All inspectory findings are confirmed.

percussion:no shifting dullness, no fluid thrills.

auscultation:normal bowel sounds are heard.


INVESTIGATIONS:


CHEST X RAY:

https://drive.google.com/uc?export=view&id=1-nfL6t8uwSY36zgpaF2DtKZ_pi6BERPT


ECG:

https://drive.google.com/uc?export=view&id=1qYlBY7QaOnrzrNEEbU_cyCDPyKDzsEo5



2D ECHOCARDIOGRAPHY:

    

TRIVIAL TR+/AR+: NO MR

NO RWMA. NO AS/MS. SCLEROTIC AV


GOOD LV SYSTOLIC FUNCTION


DIASTOLIC DYSFUNCTION. NO PAH


ULTRASOUND:

IMPRESSION:


BILATERAL RENAL CORTICAL CYSTS


BILATERAL RAISED ECHOGENECITY OF KIDNEYS


INCREASED URINARY BLADDER WALL THICKNESS


CORRELATE WITH CUE TO RULE OUT CYSTITIS 
https://drive.google.com/uc?export=view&id=1YSFWrTyw8AcG7TDAcaTthE9maGdg9ZLQ

HEMOGRAM

Hb 9.5gm/dl

Total count 11500cell/cumm

Neutrophils 91%

Lymphocytes 6%

Pcv 24.7vol%

Mcv 76 fl

MCHC 38.5%

RBC 3.25 millions/cumm




SERUM ELECTROLYTES 

12/03/23


Sodium - 118
Potassium -3.0
Chloride -72

13/03/23
Sodium - 120
Potassium -3.0
Chloride -75


14/03/23
Sodium - 119
Potassium -2.7
Chloride -78
16/03/23Sodium-116Potassium-3.8Chloride-80


ABG


pH 7.5
Pco2 28.9

Po2 88.9


SERUM CREATININE 

1.5mg/dl (0.9-1.3)


BLOOD UREA
51mg/dl (12-42)


URINARY ELECTROLYTES
Sodium - 152mmol/l
Potassium -25mmol/l
Chloride -119mmol/l

POST LUNCH BLOOD SUGAR 
219mg/dl

BLOOD SUGAR FASTING 

161mg/dl

SERUM OSMOLALITY

263mOsm/kg (275-295)

SERUM MAGNESIUM 
2.0mg/dl (1.8-2.9)


SERUM PHOSPHORUS 
2.9mg/dl (2.5-4.5)


SERUM CALCIUM 
9.0mg/dl (8.6-10.2)



LFT
ALP 212 (56-119)
TOTAL PROTEINS 4.8 (6.4-8.3)
ALBUMIN 2.6(3.2-4.6)


GLYCATED HAEMOGLOBIN 
HbA1c 7.2%
COMPLETE URINE EXAMINATION 

https://drive.google.com/uc?export=view&id=1l_WP9IzVGU7BKP6u-wVj1nYqjJAJqAuQ


BUN/CREATININE: 12.6



PROVISIONAL DIAGNOSIS:


HYPOOSMOLAR HYPERVOLEMIC HYPONATREMIA WITH HYPOKALEMIA WITH ACUTE KIDNEY INJURY(RENAL) WITH K/C/O DIABETES AND HYPERTENSION WITH MILD ANEMIA






TREATMENT:


1. FLUID RESTRICTION


2. INJ. KCL 20mEq IN 100ML NS @ 20ml/hr


3. TAB. METFORMIN 500 MG PO/BD


4. TAB. GLIMIPERIDE 1MG PO/BD


5. TAB. TELMA 40 MG PO/BD


6. TAB. MET XL 25 MG PO/BD


7. VITALS MONITORING


8. 7 POINT GRBS MONITORING.


9.TAB. CILINDIPINE 10MG PO/BD


10. INPUT OUTPUT CHARTING 


11. SYRUP. POTCHLOR 15ML PO/TIDVIN 1 GLASS OF WATER


12. INJ. ZOFER 4 MG IV/SOS


13. INJ. PAN 40 MG IV/OD


14. TAB. ALDACTONE 50 MG PO/OD


15. TAB. GLICLAZIDE 40 MG PO/OD

----------------------------------------------------------------------------------------------------------------------------------------------------

SHORT CASE 


CHIEF COMPLAINTS: 
Patient was brought to casuality with complaints of neck pain since 3 days, vomitings and headache since 1day.. 


HISTORY OF PRESENTING ILLNESS:
Pt was asymptomatic 3 days back then she developed neck pain. 
Vomitings since 1 day with 4 to 5 episodes per day, non bilious type.. 
Headache  with facial puffiness since 1 day which is of frontal type. 

PAST HISTORY:
She was bought to this hospital 1 month back for fever, sore throat, dry cough, reduced urine output, shortness of breath, pedal oedema extended till knees and  hyper pigmented macules seen over the fore head and legs , diagnosed with SLE with anti ds DNA++ , anti histone antibodies positive..

N/k/c/o Diabetes, TB or asthma., CAD, epilepsy 

Addictions : none 

FAMILY HISTORY :  no significant family history 
Surgical history: No surgeries done in past. 

TREATMENT HISTORY : treated 1 month back with
INJ AUGMENTIN 
INJ LASIX 
BUDECORT 
BETADINE GARGLING
TAB AZITHROMYCIN

PERSONAL HISTORY:
Diet: mixed
Appetite : decreased
Sleep : inadequate
Bowel movements : regular 


https://drive.google.com/uc?export=view&id=1HooSXheBs2a-dV7SnyEWlsiM__9LvA98



https://drive.google.com/uc?export=view&id=1UN-FahFqTKe6DuKo_HImX5zDVa36W8xw

https://drive.google.com/uc?export=view&id=1BACnuCH5kabpjPpDXLHikjW6psePiTyO

GENERAL EXAMINATION : patient was examined after taking consent from the attenders

Pt is conscious cooperative and coherent 

Pallor - present 
Icterus- absent
Cyanosis- absent
Clubbing- absent
Koilonychia - absent
Lymphadenopathy - absent
Edema - absent 

SYSTEMIC EXAMINATION : 

CVS : 
No thrills, no parasternal heave, 
S1, S2 +, no murmurs

RESPIRATORY SYSTEM : BAE + 
Trachea is central in position, no dyspnoea, no wheeze, vesicular breath sounds heard

ABDOMEN EXAMINATION : 
Non tender , bowel sounds heard 

CNS : No focal neurological deficit 
Oriented to person,time and place 
Speech - normal
 Signs of meningeal irritation - not present

INVESTIGATIONS
https://drive.google.com/uc?export=view&id=1wSjFFcOTsgo47ep_w9XWGd3DHuhQ-1zm
Serum electrolytes: Normal 
Serum Creatinine normal 
Blood sugar- normal 
"Blood urea is elevated":64 mg/dl(12 to 42 mg/dl)
LFT:
https://drive.google.com/uc?export=view&id=1Prjqn5CIzLQXHnQMQ0sFXMuk-dHYqzYL
Elevated alkaline phosphate-123 IU/L (42-98 IU/L)
ABG : https://drive.google.com/uc?export=view&id=1O5Wjod7zZH2YcmiiFzsegeQ775hyYopR

HEMOGRAM:
https://drive.google.com/uc?export=view&id=1_gaLGOKdS-X2zb19dBh2z_sTQFC3VJBV

Hemoglobin isReduced-10.2gm/dl (12-15 gm/dl) 
Lymphocytes are reduced-08% (20-40%) 
Neutrophils-82% (40-80%) 
-Normocytic normochromic anemia with neutrophilic leukocytosis..
MCHC is reduced-30.8%(31.5 - 34.5%) 
RDW-CV is raised - 17.8%( 11.6 - 14%) 
Rbc count is reduced-3.47millions/cumm(3.8-4.8)

PROVISIONAL DIAGNOSIS: 
SLE 

TREATMENT : 
Tab paracetamol 500mg PO/TID 
Tab warfarin 5mg PO/BD 
Tab HCQ 200mg PO/OD 
Tab azathioprine 50mg PO/BD 
Tab prednisolone PO/BD 
Inject zofer 4mg iv/BD 
syrup sucralfate 15ml PO/BD 
Monitor vitals

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