1801006067 CASE PRESENTATION

 SHORT CASE


A 13 year old Female Student came with Chief complaints of 

✓Bilateral Pedal Edema and generalised body swelling since 2 months

✓Shortness of breath 5 days back  

✓4 episodes of Vomitings 5 days back

HISTORY OF PRESENT ILLNESS -

The patient was apparently asymptomatic 2 years back (till she was 11 years old).

She was sent to hostel when she was 11 years old. After few days in the hostel she had bilateral neck swellings which were sudden in onset, 5-6 in number associated with intermittent fever and cough.

Then she was taken to a RMP who started her on ATT ( as her mother has Kochs).

She used ATT for 2 months.

After initiating ATT her fever increased so they stopped ATT and she was referred to Hyderabad. After Investigations, there was no AFB but the patient started having Complaints of knee pains and pain in the wrist joint. Then she was referred to another hospital where she was kept on Tab Wysolone and Tab HCQ (as the cause was suspected to be autoimmune). 

Later she was taken to another local hospital with complaints of joint pains, facial puffiness, pedal edema, fever, cough. Lymph node biopsy was done which was kochs negative as informed by the attender. But she was started on empirical ATT on May 2022 and her symptoms subsided. 10-15 days before taking ATT  the attendors have noticed that she was developing facial rash and Hair loss.

The patient was asymptomatic 2 months back then she developed bilateral pedal edema

5 days on she has shortness of breath on exertion and also she had 4 episodes ( 5 days back) of Vomitings with food particles as content, non bilious, non projectile, and not associated with any blood.

PAST HISTORY :

She is a known case of TB (1year back used ATT for 6 months)

N/k/c/o Hypertension, DM, epilepsy, Asthma 

BIRTH HISTORY:

She is the 1st child 

2nd degree consanguineous marriage 

Born in 2010

LSCS - delivery 

Father has no idea about immunisation status

FAMILY HISTORY :

2014 patient's mother was diagnosed with TB-expired in 2022 September (did not use ATT regularly)

PERSONAL HISTORY:

Diet - Mixed

Appetite - Decreased 

Decreased urineoutput 

Sleep - adequate 

Addictions - None

TREATMENT HISTORY :

Used Anti Tubercular therapy for 6 months for extra pulmonary tb.

GENERAL EXAMINATION : 

The patient is conscious, coherent, cooperative, and well oriented to time, place and person. 

Ill built and undernourished 

Pallor is present 




Edema of Lower Limbs is present 




No icterus, cyanosis, clubbing, lymphadenopathy 

VITALS:

Temp: 98.4 F

PR: 126 bpm

BP: 130/90 mm Hg

RR: 26 cpm

SPO2: 98% 

SYSTEMIC EXAMINATION : 

Patient is examined in a well lit room and in a sitting position

PER ABDOMEN EXAMINATION -

Inspection -

Shape - slightly distention.

Umbilicus - Inverted

Equal symmetrical movements in all the quadrants with respiration.

No visible pulsation,peristalsis, dilated veins and localized swellings.

Palpation-

Soft, tenderness in right and left Hypochondrium, epigastrium.

Percussion

Fluid thrill and shifting dullness present

Auscultation

Bowel sounds heard

No bruit or venous hum.

RESPIRATORY SYSTEM:

Bilateral Air entry present

Vocal resonance is decreased

Dull note all over. 

C V S :

S1,S2 heard

Pericardial rub is Present

No murmurs.

C N S :

No focal neurological deficits 

HIGHER MENTAL FUNCTIONS- Normal

Memory intact

CRANIAL NERVES :Normal

SENSORY EXAMINATION :

Normal sensations felt in all dermatomes

MOTOR EXAMINATION :

Normal tone in upper and lower limb

Normal power in upper and lower limb

Normal gait

REFLEXES-

Normal reflexes elicited- biceps, triceps, knee and ankle reflexes elicited

CEREBELLAR FUNCTION :

Normal function

No meningeal signs were elicited

CLINICAL IMAGES -





INVESTIGATIONS-

Previous Investigations as dated on 9-10-21

ANA- Equivocal

Anti dsDNA- Positive

Fever Chart -


Complete Urine Examination--Albumin- ++

ESR- 70 mm/1st hour
Hemogram
Hb- 6.8gm/dl
PCV- 23.3 vol%
MCV- 77.4 fl
MCH- 22.6 pg
MCHC- 29.2%
RBC- 3.01 millions/cumm
Platelet Count-1.20 lakhs/cumm
Impression - Dimorphic anaemia with thrombocytopenia

S.Creatinine- 0.6 mg/dl
Blood Urea- 45 mg/dl
Spot Urine Protein - 393 mg/dl
Spot Urine Creatinine- 37.8 mg/dl
Ratio-- 10.3
Spot Urine Protein- 10gm/dl

USG-

Liver,gallbladder,pancreas,spleen, uterus,ovaries normal

Moderate ascites

Bilateral pleural effusion

Moderate pericardial effusion

Bilateral grade 2 RPD changes

Chest X-ray

28-9-20


14-3-22


2D Echo




ECG-
14/3/23


15/3/23


DIAGNOSIS : 

?Autoimmune disease

? Glomerulonephritis secondary to  Lupus Nephritis

? Systemic Lupus Erythematosus

TREATMENT -

Fluid restriction ( 1.5 L/day)

Salt restriction (1.2 GM/day)

Inj lasix 40mg IV BD

Inj Monocef 1gm IV BD

Inj Methyl prednisolone 250mg in 100ml NS IV OD

Tab Aldactone 25mg PO OD

Tab Shelcal 500mg PO OD

Vitals monitoring


---------------------------------------------------------------------------------------------------------

Long case


A 52 year old male patient who is a vegetable vendor by occupation and resident of miryalaguda came to the casualty with chief complaints of shortness of breath since 6months.

HISTORY OF PRESENTING ILLNESS:

Patient is apparently asymptomatic 6months ago then he developed shortness of breath which is insidious in onset, intially it was for heavy work (class 1-NYHA) progressed to producing symptoms even on rest (class 4-nyha) for which he went to a local hospital in miryalguda 1month back and diagnosed to have acute kidney injury and have prescribed him bronchodilator(inhaler) which gave him temporary relief ; there are no aggrevating factors; associated with orthopnea,trepopnea, PND and nocturnal cough since 1month, decreased frequency of micturation(4 to 5 times a day usually now only for 2 times/day) since 20 days and not associated with palpitations, chest pain, syncope, fever.

Patient presented here with (class 2-nyha).

Patient has bilateral pedal edema extending upto the knee which is pitting type since 1 month which gradually progressed and he also noticed puffiness of face since 20 days.

DAILY ROUTINE:

Patient wakes up at 6 am and have a cup of tea and eats breakfast at 8am and goes to work evng he'll have cup tea and has dinner at 8pm.

Since 1 month he is not able to do his regular physical activity. He couldn't lift heavy weight and having Dyspnea with regular physical activity. 

PAST HISTORY:

No history of similar complaints in the past.

He is not a known case of Hypertension, diabetes mellitus, asthma, epilepsy, TB, CAD, CVD, thyroid abnormalities.

He has history of back pain for which he is on analgesics(nsaids??) since 1 year weekly (stopped 1 month back.)

Patient underwent hernia surgery on both the sides 6 years back on right side and 4 years back on the left side.

PERSONAL HISTORY:

Diet: Mixed

Appetite:Normal 

Sleep:Adequate

Bowel and bladder movements: regular 

Addictions: occasional alcoholic since 20 years(90ml) and gutka since 20 years.

FAMILY HISTORY:not significant.

GENERAL EXAMINATION:

Patient is conscious coherant cooperative, Moderately built and moderately nourished Pallor-present 

Icterus-absent 

Cyanosis-absent 

Clubbing-absent 

Generalised lymphadenopathy-absent

B/L Pedal edema-present 

Vitals:

Temperature- afebrile

Pulse rate-68 bpm

Respiratory rate-16cpm

Blood pressure -130/70mm of hg

SYSTEMIC EXAMINATION:

Cardiovascular system:

Inspection:

Chest wall- symmetrical

No Precordial bulge, Pectus carinatum/excavatum 

No scar, No sinuses

Apex beat felt at 6th ICS shifted laterally 2cm left to the mid clavicular line.

Jvp:Elevated 

No Parasternal heaves or thrill.

auscultation: 

    pansystolic murmur(s1- faintly heard), s2 heard

respiratory system

bae-present,normal vesicular breath sounds heard

fine crepitations on both the side

central nervous system

hmf- intact

sensory- intact

motor system-normal

cranial nerves-intact

abdominal examination

soft and non tender, no hepatomegaly, spleen is not palpable.

Clinical Images-







Provisional diagnosis:

Heart failure (HFREF) with acute kidney injury. 

Investigations:

HEMOGRAM

Haemoglobin - 12.8 gm/dl.

Total count - 9,900 cells/ column.

Neutrophils - 79%.

Lymphocytes - 09%.

Eosinophils - 02%.

Monocytes - 10%.

Basophils - 00%.

PCV- 37.4 vol%.

M C V - 87.0 fl.

M C H - 29.8 pg.

M C H C - 34.2%.

RDW-CV - 11.9%.

RDW-SD - 38.6 fl.

RBC count - 4.30 millions/cumm.

Platelet count - 3.60 lakhs/ cumm.

 SMEAR

RBC - Normocytic normochromic.

WBC - with in normal limits.

Platelets - adequate in numbet and distribution.

Hemoparasities - no hemoparasities seen.

Impression - normocytic normochromic blood picture.

Blood urea - 96 mg/dl

Serum creatinine - 4.8 mg/dl

2D Echo-

Conclusion - Moderate to sever LV dysfunction.

-Daistolic dysfunction .

Chest X-ray 


ECG





Treatment:

Inj. LASIX 40mg BD

Tab. ECOSPRIN-av 75/20mg PO

Tab.MET-xl 12.5 PO OD

Inj.THIAMINE 200mg I.v BD

Tab. PANTOP 40mg PO OD

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