1801006070 CASE PRESENTATION

long case


 29 year old female customer service executive came to the hospital with complaints of swelling of both legs and both eyes since 3 days.

HISTORY OF PRESENT ILLNESS


In 2017 she had generalised body aches and joint pains involving multiple large joints of which elbow and knee joints  troubled her associated with generalised body aches .

she even noticed hair loss without scarring and oral ulcers . Later , she was diagnosed with autoimmune disorder and initiated on hydroxychloroquine , azathioprine , wysolone  .

She reported that her joint pains and hair loss were not improving  with above medication . She had multiple hospital visits and admissions for joint pains and body aches which bothers her from doing her activities .


Two months back she had pedal edema , sudden onset of shortness of breath initially on exertion then she was diagnosed with hypertensive emergency admitted and discharged with antihypertensives . Patient stopped AZA as advised by doctor  except antihypertensive .  since yesterday she had shortness of breath initially on exertion which rapidly progressed to sob at rest 


No small joint pains no colour change /paraesthesia so fingers on exposure to cold



PAST HISTORY 

Known case of SLE and is on 

Rabeprazole + domperidone 

Tab orofer xt po/od 8am 

Tab shelcal 500mg po/od 

Tab sodium bicarbonate 500mg po/bd 

Tab nicardia 20mg po/tid 

Probiotics 

She’s not a known case of diabetes, CAD, asthma, tuberculosis.

PERSONAL HISTORY 

Her day starts at 7 AM . She used to get ready for  work and went to office at 8 AM . have breakfast at office at around 10 am . Her work was more of  attending client calls with 1-2 breaks in between till 6 PM.Sleeps at 11 pm . Since one month , she had quit her job due to regular dialysis.

Appetite :lost 

Sleep : Adequate 

Bowel movements : Reduced 

Micturition : Decreased urine output 

No addictions 

 MENSTRUAL HISTORY 

Age of menarche:12 years.

Menstrual cycles :Her Menstrual cycles were irregular since 2 months. 

Her last Menstrual period was Dec 25th 2022 

Obstetric history:- para 2 live 1 


GENERAL EXAMINATION 

Pallor: present 

Flat nails

Non-scarring alopecia 


Hyperpigmented discoid rashes on face 


Periaural black discolouration of oral mucosa and palate 


Mild pedal edema 


No icterus, cyanosis, lymphadenopathy







Vitals:

Temperature: 98.2 F 

Pulse rate: 131bpm

Respiratory rate: 24/min 

BP: 180/110mmhg

Spo2: 98%

GRBS: 98mg/dl

SYSTEMIC EXAMINATION 

CVS 

S1 ,S2 present 

No murmurs 


RESPIRATORY SYSTEM 

Bilateral air entry present 

Normal vesicular breath sounds heard 

No dyspnoea and no wheeze 


PER ABDOMEN

Shape of abdomen: scaphoid 

Tenderness present around umbilicus 

Liver and spleen are not palpable 


CNS

Patient is conscious 

Speech: normal 

Cranial nerves: normal

Motor and sensory system: normal 

Glassgow coma scale: E4 V5 M6


INVESTIGATIONS 


15.03.2023

Blood urea -79 mg/dl (N=12 to 42 mg/dl)

Serum creatinine-4mg/dl(N0.6 to 1.1)

Serum electrolytes-

Na :141mEq/L(N-136 to 145)

K:3.5mEq/L(N:3.5 to 5.1)

Cl:102mEq/L(N=98 to 107)

Ionized ca+2:1.01mmol/L.

14.02.2023

HEMOGRAM:

Hb 8.5gm/dl.

Total count:12000 cell /cumm

Neutrophils:83 %

Lymphocytes:11%

Pcv:24.3 volume %

Platelets :l.lL / cumm.

Impression :Normocytic normochromic anemia  with neutrophilic lymphocytes and thrombocytopenia.

Renal function test:

Blood Urea:157mg/dl

Serum Creatinine :6.9 mg/dl.



DIAGNOSIS 

Chronic renal failure secondary to lupus nephritis 



TREATMENT 


Tab Nicardia 30mg,po/tid

Tab lasix 40mg , po/bd .

Tab wysolone,po/bd.

Tab azathioprine 50 mg po/ od

Tab hydroxychloroquine 200mg po/od. 

Tab Met xL 25 mg ,po/od. 

Tab nodosis 500mg po/od.

Tablet  shelcal 500mg po/od

Tab orofer xt po/od

Tab Pan 40mg po/od.


---------------------------------------------------------------------------------------------------------

short case


42 year old male farmer from kistapuram  came with chief complaints of 
1) Headache since 3 days 
2) Dragging pain of limbs since 3 days 

History of presenting illness : 
Patient was apparently asymptomatic 1 month back . Following pesticide spraying(Monocrotophos)his farm without any protective equipment , he complained of headache next day followed by episode of vomiting . He came to hospital and took some medications and been on medications for 25 days since then . 
3 days back his medicines were over . Then he complained of dragging pain in his upper and lower limbs and headache . Headache is mild to moderate , relieves on taking some rest and aggaravated on working . Dragging pain of upper and lower limbs is constant . 

Past History :
Not a known case of Diabetes Mellitus , Hypertension , Asthma , Epilepsy , CAD 

Daily Routine
He daily wakes up at 6AM and  eats at 8:30AM then he go to field and have lunch at 1:00PM  and go back to field and return home by 7:00AM ,have dinner and sleep at 9:00PM.

Personal History :

Diet - Mixed
Appetite - Good
Bowel & Bladder - Regular 
Sleep - Adequate 
No addictions

No significant Family history 

No significant treatment history 

General Examination: 

Patient is conscious , cooperative , well oriented to time , place , person . Moderately built and nourished .

Patient is examined after taking informed consent in a well lit room .

Pallor - present 


Icterus - Absent

Cyanosis - Absent 
Clubbing - Absent
Lymphadenopathy - Absent
No pedal Edema 


VITALS :
Temperature - Afebrile 
Pulse rate - 70 bpm
Respiratory rate - 16 cpm
Blood pressure - 120/60 mm Hg

 CNS EXAMINATION:

Right handed person 

HIGHER MENTAL FUNCTION :

Counsious ,oreinted to time place person
Speech normal
Behaviour normal
Memory intact 
Intelligence normal 

REFLEXES: 

-Corneal present 

-Conjunctival  present 

-Abdominal: present 

-Plantar: present 


Deep tendon reflexes :


 
Knee jerk - 2+

Gait :- normal 

Kernig’s sign negative 
Brudzinski sign negative 

Cvs
s1 s2 heard 
no murmurs
apex beat at mid clavicular line in 5 th intercoastal space.
Respiratory system 
I: Chest bilaterally symmetrical, all quadrants
moves equally with respiration
P: Trachea central, chest expansion normal
P: Resonant
A: B/l equal air entry
no added sounds

PerAbdominal examination :-
I :normal
P :soft non tender
No organomegaly

Review of Literature : 



 Provisional diagnosis-

Headache probably secondary to Monocrotophos (pesticide)with generalized body pains .

 Investigations 
Haemogram
Complete urine examination
RFT,LFT.



Treatment received 

1) Inj.1amp Optineuron in 500ml 0.9% NS IV over 30 minutes.
2) Tab . Aceclofenac PO BD 
3) Tab . Naproxen 200mg PO BD
4) Tab . Zofer 4mg PO BD 
5) Tab . MVT PO OD

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