1801006072 CASE PRESENTATION

Long Case 


Chief complaints 

A 50 year old male farmer by occupation came to opd with chief complaints of 

1. SOB since 10 days

2.Edema of both upper and lower limb since 6 days



History of presenting illness-

                  SEQUENCE OF EVENTS 


Patient was apparently asymptomatic 14 years ago then he had a history of fall from tree where he got back pain and used medication for that



                                         ↓                                       8 years ago(2015)

         He was diagnosed with diabetes mellitus type 2                           



                                         

2 years ago(2019)- Developed fever cough and loss of appetite diagnosed with TB and took ATT for 6 months



                                       

1 year ago - he met with fire accident after that he noticed swelling in legs for which he diagnosed with 

ckd  


                                       

 Jan 2023 - In 2023 Jan he developed shortness of breath grade 3 



                                       

 March 2023-       10 days back he had sudden onset of difficulty in breathing which has progressed to 

Grade 4  orthopnea present, and Edema of both upper and lower limbs For 6 days 

Lower limb edema which is pitting type (grade 4 ) up to the thigh.

In a private hospital And was referred to our hospital for further management.





Past history-

Known case of diabetes mellitus since 8 years and was on medication- metformin


Not a known case of; Hypertension, thyroid, or Asthma. 

No history of any surgeries in the past. 

Drug history:- intermittent use of NSAIDS for the past 14 years. 



Personal history 


Mixed diet 

Appetite was normal

Bowel and bladder - decreased urinary output since 6 days 

Sleep adequate 

Addictions 

alcohol (daily)stopped 2years ago ,now occasionally 


Family history- not significant 

General physical examination 

Patient is conscious coherent and cooperative well oriented to time place person

Moderately built and moderately nourished.






        Imaginary pillow effect.



Pallor-absent 

Icterus-absent

Cyanosis-absent

Clubbing-absent

Lymphadenopathy-absent

Pedal edema- seen bilaterally (pitting type)



Vitals:—

Temperature- afebrile 

Pulse rate- 103bpm

RR- 35cpm

Blood pressure-150/90 mmhg

Grbs:- 203mg/dl

SpO2:- 97% @room air


Mild JVP raise is seen



SYSTEMIC EXMINATION-


Cardiovascular system:-


CARDIOVASCULAR SYSTEM:- 

INSPECTION:-

Appears normal in shape

Apex beat is not visible

No Dilated veins, scars, sinuses

PALPATION:

1- All inspector findings were confirmed.

2-Trachea is central.

APEX BEAT at 5TH INTERCOSTAL SPACE IN 1 cm LATERAL TO MID CLAVICALE

No palpable murmurs (thrills)

PERCUSSION:- 

 Heart borders are normal limits.

AUSCULTATION:-

S 1; S 2 heard in ALL THE AREAS 


Mild JVP Raise is seen


RESPIRATORY SYSTEM:-

INSPECTION:- Chest appears symmetric

    No Dilated veins, scars, sinuses

PERCUSSION -

    


Auscultation:—

NVBS are less heard in infraaxillary,infrascapular and inter scapular regions.



PER ABDOMEN:- 

no tenderness

no palpable organs

bowel sounds - present


CNS EXAMINATION:- 

The patient is conscious. 

No focal deformities. 

cranial nerves - intact 

sensory system - intact


motor system - intact


INVESTIGATIONS:- 

7/3/ 23:- 

HAEMOGLOBIN %- 10.0 gms %

PCV :- 31.8 vol% 

8/3/23:- 

HAEMOGLOBIN - 11.3 gms % 

PCV :- 36.1 vol%

9/3/23:- 

HAEMOGLOBIN %- 11.0 gms %

PCV  - 34.5 vol%

SERUM CREATININE - 5.6 mg/dl.

10 /3/23 :- 

ULTRASOUND:- 

IMPRESSION:- B/L GRADE IN RENAL PARENCHYMAL CHANGES

B/L MODERATE PLEURAL EFFUSIONS

MILD ASCITES 

SERUM CREATININE

5.9 mg/dl 

SERUM POTASSIUM

3.4 mEq/L

HAEMOGLOBIN % - 10.6 gm 

PACKED CELL VOLUME:- 34.2 vol% ( decreased)

11/3/23:- 

SERUM CREATININE:- 5.9 mg/dL


Then referred to our hospital

13/3/23 :- 

Serology:

    HIV: NEGATIVE 

    Anti-HCV antibodies:- NON-REACTIVE

    HbsAg:- NEGATIVE 

    RANDOM BLOOD SUGAR: 125mg/dl

    CUE:- NORMAL 

    S.UREA: 64mg/dl (N:- 12-42mg/dl)

    S. CREATININE: 4.3 mg/dl

    S. Na+: 138

    S. K+: 3.4 (3.5-5.5)

    S. Cl-: 104

CBP:- 

    Hb:- 12.6 gm/dl

HbA1C: 6.5%

FASTING BLOOD SUGAR:- 93 mg/dl 

POST-LUNCH BLOOD SUGAR:- 152 mg/dl 

Liver function tests:-

Total bilirubin-0.9mg/dl

Direct bilirubin-0-1mg/dl

Indirect bilirubin-0.8mg/dl

Alkaline phosphatase- 221 u/l

AST-40u/L

ALP- 81u/L


Chest X-ray 





ECG 

    


Left axis deviation  
Normal sinus rhythm 
Mild LVH


USG CHEST: 

IMPRESSION:

BILATERAL PLEURAL EFFUSION (RIGHT MORE THAN LEFT) WITH UNDERLYING COLLAPSE.

USG ABDOMEN AND PELVIS:

MILD TO MODERATE ASCITES


RAISED ECHOGENICITY OF BILATERAL KIDNEYS



2D echo:-

    Mild LV dysfunction-present

    MR +ve, TR +ve (moderate)










Provisional diagnosis:-

-Heart failure with mid range ejection fraction

With Acute kidney injury on chronic kidney disease (NSAID induced or diabetes induced).

With old pulmonary kochs (2 yrs ago)

And bilateral pleural effusion (left side is more than right side)


Treatment:—

-Fluid restriction less than 1.5lts per day.

-salt restriction less than 1.2gm perday

-INJ Lasix 40 mg IV/BD.

-TAB MET XL 25mg PO/OD

-TAB Cinod 5 mg PO/OD.

-INJ human actrapid insulin SC/TID

-INJ PAN 40 mg IV/OD

-INJ ZOFER 4mg IV

- vitals monitoring

-TAB Ecosprin AV 75/10 mg PO/HS.


---------------------------------------------------------------------------------------------------------------

short case


CHIEF COMPLIANTS


A 64 year male patient presented with cheif compliants of:


Cough since 10 days

Loose stools since 10 days

Hiccups since 7 days

Inability to speak since 4 days 

fever 4 days back

loss of appetite since 3 days


HISTORY OF PRESENT ILLNESS

patient was apparently asymptomatic 10 days back then he developed diarrhoea -5 episodes/day for 1 day which relieved on medication.Then he developed having hiccups since 7 days and anorexia for 3days.since 25/12/22 he is unable to talk.

        



PAST HISTORY

h/o panic attack one month back secondary to family issues 


  -DM2 since 6 yrs ,

 on medication :tab Metformin OD , tab Glimiperide OD


 -NO HISTORY OF HTN, TB, Asthma, epilepsy, CAD, CVD


Personal History :- 


Appetite - reduced


Diet - Mixed 


Sleep - adequate


Bowel and bladder movements - incontinence 


Addictions: Occasional alcoholic ( during functions ) ,chews tobacco daily


Allergies : No allergies 


Family history:


Mother is a known case of TB 5years back who is treated adequately.



GENERAL EXAMINATION

Patient is unconscious ,incoherent , uncooperative

 Moderately Built and Moderately Nourished .


Pallor : present 

Icterus : absent 

Cyanosis: absent 

Clubbing : absent 

Lymphadenopathy : absent 

Edema : absent


 Vitals :- 


Temp: Afebrile 

BP : 100 / 50 mmHg 

PR : 120 bpm 

RR : 16 cpm 

SPO2 : 98 % at RA

GRBS : 193 mg/dl 


Fever 

SYSTEMIC EXAMINATION: 


CNS examination :-

HIGHER MENTAL FUNCTIONS

State of consciousness : unconscious 

Speech : incoherent 


Sensory system :- 


Pain - Normal 

Temp - normal


Cranial nerves :  

Not elicited patient not cooperative



CNS 


Reflexes :-

Biceps + +

Tricep s + +

Supinator + +

Knee +

Ankle. ++

Flexor. Plantar. Plantar 


Finger nose in coordination - no 

Heel knee in coordination - no


CVS : S1 S2 + ,no murmurs ,no thrills 


Respiratory System : decreased air entry on left side . Crackle sound are heard. Position of trachea - central.


Per abdominal examination:- 


Soft , non tender , no signs of organomegaly




Chest X-ray 






INVESTIGATIONS:


CSF ANALYSIS


Sugar  51 mg/dl (normal 60-90mg/dl)

Protein 203mg/dl( normal 10- 45mg/dl)

Chloride 121 mmol/L (116-127mmol/l)


CSF CELL COUNT

Colour - colour less

Appearance - slightly cloudy

Total cells - 90 cells /cumm

Lymphocytes -60%

Neutrophils - 40%


COMPLETE URINE EXAMINATION


Colour - pale yellow

Appearance - clear

Reaction - acidic

Specific gravity - 1.010

Albumin -nil

Sugar -nil

Bile salts - nil

Bile pigments- nil

Pus cells - 2-3cells(normal 0-5/HPF)

Epithelial cells- 2-3 cells(normal 0-5HPF)

RBC -nil (normal 0-5/HPF)

Crystals-nil

Casts-nil

Amorphous deposits-absent


BLOOD UREA -124mg/dl(normal 17-50mg/dl)


APTT

  

APTT TEST- 31sec(normal 24- 33sec)


Bleeding and clotting time


Bleeding time- 2min 30sec(normal2 -7 min)

Clotting time- 5min (normal 1- 9min)


PROTHROMBIN TIME - 15sec ( normal 10 -16 sec)


MRI BRAIN PLAIN 

DIFFUSE CEREBRAL ATROPHY


BLOOD SUGAR 159mg/dl 





DIAGNOSIS 


    Altered sensorium secondary to tuberculous

meningitis 


Management:-

1) IVF 0.9 %NS IV @ 50 ml / hr 

2) Inj , 1 amp Optineuron in 500 ml NS IV /OD 

3) tab Ecosprin AV 75/10 RT / OD / HS

4) GRBS monitoring 6 th hrly 

5) Inj Thiamine 200 mg IV/BD in 100 ml NS 

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