long case
A 65years old male , alcohol ( Sara ) seller by occupation, resident of narketpally came with chief complaints of
Fever since 3 days
Shortness of breath since 3 days
HISTORY OF PRESENTING ILLNESS
- Patient was apparently asymptomatic 3 days back and then he developed fever which was sudden in onset high grade continuous ,associated with chills and relieved on medication
- H/o shortness of breath since 3 days which was sudden in onset , aggravated during walking and relieved on rest .
- H/o cough which was insidious in onset , intermittent , associated with sputum which was scanty in amount and non foul smelling .
- No h/o hemoptysis .
- No h/o weight loss.
- No h/o headache , body pains.
- No h/o vomiting , diarrhea and constipation ,abdominal pain .
- No h/0 decreased urine , burning micturition , increased or decreased frequency of urine
- No h/o fatigue, orthopnea , pnd , palpitations, exertional dyspnea .
PAST HISTORY
He is a known case of diabetes and hypertension since 7 years , for which he is using
Tab. METFORMIN 500 mg OD
Tab. AMLONG 5mg OD
- 6 months back , he developed bilateral lower limb swelling which was pitting type , and was diagnosed with left renal calculi & CKD
-No h/o asthma , tuberculosis , epilepsy , thyroid , coronary artery disease .
-No history of surgeries in the past
PERSONAL HISTORY
- Patient has mixed diet and decreased appetite
- Adequate sleep
- Regular bowel and bladder movements
- Patient consumed the same alcohol that he sold since 20 yrs
FAMILY HISTORY
No relevant family history
ALLERGIC HISTORY:-
NO ALLERGIES FOR ANY KIND OF DRUGS AND FOOD ITEMS.
GENERAL EXAMINATION
Patient is conscious coherent and cooperative, well oriented to time place and person
Pallor - present
No signs of cyanosis , clubbing , lymphadenopathy and pedal edema
VITALS :
Temp - afebrile
PR - 80 bpm regular ; normal volume and character.
RR - 21 cpm
BP - 110/70 mm hg in right hand supine position.
SYSTEMIC EXAMINATION
RESPIRATORY SYSTEM :
On Inspection
-Shape of the chest - elliptical ,
Asymmetrical chest
- Trachea Central
- No retractions
- Decreased movements on the right side of chest
- No visible scars , sinuses , engorged veins and pulsations
On Palpation
Inspectory findings are confirmed
No local rise of temperature
No tenderness
Trachea Central
Reduced chest expansion on right side
Ap diameter - 16 cm
Transverse diameter -23 cm
Tactile vocal fremitus
Areas. Right. Left
Supraclavicular present. Present
Infraclavicular present. Present
Mammary diminished present
Inframammary diminished. Present
Axillary present. Present
Infra axillary diminished. Present
Suprascapular present. Present
Infrascapular diminished. Present
Interscapular diminished. Present
On Percussion
Areas. Right. Left
Supraclavicular. Resonant. Resonant
Infraclavicular. Resonant. Resonant
Mammary. Dullnes. Resonant
Inframammary. Dullness. Resonant
Axillary. Resonant. Resonant
Infra axillary. Dullness Resonant
Suprascapular. Resonant. Resonant
Infrascapular. Dullness. Resonant
Interscapular. Dullness. Resonant
On auscultation
-Bilateral air entry present
-Decreased breath sounds on the right side inframammary, infrascapular , interscapular and infra axillary regions .
Normal breath sounds in all other areas
- Right infra axillary and infrascapular crepts are heard .
CARDIOVASCULAR SYSTEM :
On Inspection
Shape of the chest elliptical
No raised Jvp
Apical impulse - not seen
Precordial bulge not seen
No visible sinuses , scars , engorged veins , pulsations
On Palpation
Apex beat felt at left 5th intercostal space in mid clavicular line
No thrills and parasternal haeves
On Auscultation:-
S1 ; S2 heard ; no murmurs
PER ABDOMEN
On Inspection
- Umbilicus is central and inverted
- All quadrants are moving with respiration symmetrically
- No visible scars , sinuses , and pulsations
- No hernial orifices
- External genitilia normal
On Palpation
- No local rise of temperature and tenderness
- Abdomen is soft and non tender
- No organomegaly
On Percussion
- Tympanic note heard over the abdomen
On Auscultation
-Bowel sounds are heard
-No bruit
CENTRAL NERVOUS SYSTEM :
Patient is conscious coherent and cooperative
Speech is normal
No signs of meningeal irritation
Cranial nerves - intact
Sensory system normal
Motor system: normal
Signs of meningeal irrigation:- absent
PROVISIONAL DIAGNOSIS
Right pleural effusion
? Synpneumonic effusion
CKD since 6 months .
Diabetes and hypertension since 7 years.
INVESTIGATIONS:-
Haemogram
Hb - 11.4 gm/dl
RBC - 4.7 millions/cumm
Total count - 7200 cells/cumm
Platelet count - 3.0 lakhs/cumm
PCV - 41 vol%
Blood sugar random
Rbs - 115mg / dl
Complete urine examination
Color - pale yellow
Appearance - clear
Albumin - +
Sugars - nil
Pus cells - 2 to 3
Renal function test
Blood Urea - 113mg/dl
Serum Creatinine - 7.3mg/dl
Serum electrolytes
Na+ : 130 mEq/l
K+ : 3.7 mEq/l
Cl- : 101 mEq/l
Liver function test
Total bilurubin - 0.3 mg/dl
Direct biluribin - 0.1 mg/dl
SGOT - 20 IU/l
SGPT - 24 IU / l
ALP - 110 IU / l
Total proteins - 6.9 gm /dl
X - ray
On admission pleural tap was done and 300 ml of pleural fluid was drained
800 ml of pleural fluid was drained on pleural tap on 3rd day and post x- ray
Pleural fluid and sputum CBNAAT was negative
Pleural fluid cytology :
Microscopy - smear shows many lymphocytes with few neutrophils. No atypical cells seen
Pleural fluid culture negative
Pleural fluid analysis
Total cells - 1800 ( 70% neutrophils )
Color - pale yellow
Appearance - cloudy
ADA - 26 IU / l
Protein - 4.6
LDH - 111
Serum LDH - 204
Serum protein - 6.7
Light's criteria
Pleural fluid protein / serum protein : 4.6/6.7 = 0.68
Pleural fluid LDH / serum LDH:
111/204 = 0.54
Interpretation: Exudative pleural effusion
USG Findings
Lung : Pleural effusion on right side and consolidation in the lower lobe
Kidney : multiple calculi noted in lower pole of left kidney.
FINAL DIAGNOSIS
Right lower lobe pneumonia with pleural effusion with CKD and renal calculi since 6 months .DM and HTN since 7 years .
Treatment :-
Inj Augmentin 1.2gm IV BD
Iv fluids NS urine output+30ml/hr
Inj pantop 40mg OD
Furosemide 20mg
Salt restriction.
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short case
CHIEF COMPLAINTS
• Pain in the left side of abdomen on and off since 1 year.
HISTORY OF PRESENTING ILLNESS
• Patient was apparently asymptomatic a year back then she started developing pain in left hypochondrium which is insidious in onset intermittent & dragging type. since last one year she is having 1-2episodes of pain every month lasting for 30-60 min.
•c/o frequent onset of fever (once in 15-20 days) since 1 year, for which she visited a local hospital and found to be having low hemoglobin & started oral iron (used for one month) for which she had black coloured stools.
•c/o shortness of breath since one year ( Grade III)
•c/o early fatigability,
•decreased appetite since 14 years of age
•No H/o chest pain, pedal edema
•No H/o orthopnea, PND
•No H/o cold , cough
•No bleeding manifestations
•No c/o weight loss
PAST HISTORY
•Not a known case of Hypertension , Diabetes mellitus , Tuberculosis , asthma , thyroid disorders, epilepsy , CVD , CAD
• No H/o surgeries in the past
FAMILY HISTORY
•No significant family history
PERSONAL HISTORY
• Diet - mixed
• appetite - decreased
• sleep - adequate
• bowel and bladder - regular
• No addictions and no known allergies
MENSTRUAL HISTORY
• age of menarche - 12 yrs
• Regular cycles , 3/28 , changes 3-4 pads per day.
• No gynecological problems
GENERAL PHYSICAL EXAMINATION
• patient is conscious, coherent, cooperative and well oriented to time, place and person.
• moderately nourished
• No pallor, icterus, cyanosis, clubbing, lymphadenopathy,edema.
VITALS
Temperature : afebrile
Respiratory Rate:18 cycles per minute
Pulse rate : 78 bpm
Blood pressure :110/70 mmHg
SYSTEMIC EXAMINATION
PER ABDOMEN :
• inspection
Shape - flat , no distention
Umblicus - inverted, round scar around umblicus
No visible pulsations,peristalsis, dilated veins
Visible swelling in the left hypochondrium , 6cm×4cm in size, oval shape, smooth, skin over swelling is normal
Hernial orifices are free
• Palpation
No local rise of temperature and tenderness
Spleen palpable ( moderate splenomegaly) 5cm below it's costal margin by
CLASSICAL METHOD
Other methods
Dipping method(in ascites)
Bimanual method
No palpable liver
•Percussion
liver span -12 cm
Spleen - dullness extending to umbilical region
Fluid thrill and shifting dullness absent
Auscultation
Bowel sounds: present
CARDIOVASCULAR SYSTEM:
•Inspection
Shape of chest- elliptical shaped chest
No engorged veins, scars, visible pulsations
•Palpation
Apex beat can be palpable in 5th inter costal space medial to mid clavicular line
No thrills and parasternal heaves can be felt
•Auscultation
S1,S2 are heard
no murmurs
RESPIRATORY SYSTEM:
•Inspection
Shape of the chest : elliptical
B/L symmetrical ,
Both sides moving equally with respiration
No scars, sinuses, engorged veins, pulsations
•Palpation
Trachea - central
Expansion of chest is symmetrical.
•Auscultation
B/L air entry present . Normal vesicular breath sounds
CNS:
•HIGHER MENTAL FUNCTIONS-
Normal
Memory intact
•CRANIAL NERVES :Normal
•SENSORY EXAMINATION
Normal sensations felt in all dermatomes
•MOTOR EXAMINATION
Normal tone in upper and lower limb
Normal power in upper and lower limb
Normal gait
•REFLEXES
Normal, brisk reflexes elicited- biceps, triceps, knee and ankle reflexes elicited
•CEREBELLAR FUNCTION
Normal function
No meningeal signs were elicited
•Provisional diagnosis:-
Splenomegaly with anemia.
4/03/2023
HAEMOGLOBIN- 8.7 gm/dl
TOTAL COUNT - 2130 cells/cumm
pcv - 30.0
MCV - 78.9
MCHC - 28.6
smear- Anisocytosis with normocytes microcytes tear drops pencil forms and macrocytes
impressions -Pancytopenia
7/03/2023
HAEMOGLOBIN- 9.2 gm/dl
TOTAL COUNT - 2000 cells/cumm
pcv - 33.4
MCV - 82.1
MCHC - 27.5
smear- Anisocytosis with normocytes microcytes tear drops pencil forms and macrocytes
impressions -Pancytopenia
9/03/2023
HAEMOGLOBIN- 9.8 gm/dl
TOTAL COUNT - 2600 cells/cumm
pcv - 34.3
MCV - 80
MCHC - 28.6
smear- Anisocytosis with normocytes microcytes tear drops pencil forms and macrocytes
impressions -Pancytopenia
12/03/2023
HAEMOGLOBIN- 8.8 gm/dl
TOTAL COUNT - 2000 cells/cumulative
lymphocytes - 42%
pcv - 30.1
MCV - 80.3
MCH - 23.5
MCHC - 29.5
RBC 3.75 millions/cumm
smear- Anisocytosis with normocytes, microcytes tear drops ,pencil forms and macrocytes
impressions -Pancytopenia
13/03/2023
HAEMOGLOBIN- 8.7 gm/dl
TOTAL COUNT - 2000 cells/cumm
pcv - 29.8
MCV - 80.5
MCH - 23.5
MCHC - 29.5
RBC - 2.70millions /cumm
smear- Ansocytosis with normocytes microcytes tear drops pencil forms and macrocytes
impressions -Pancytopenia
APTT
Result- 41s
BLOOD UREA- 26 mg/dl
BLEEDING AND CLOTING TIME
bleeding time - 2min
clotting time -4min
BLOOD GROUPING AND RH TYPE-B positive
PROTHROMBIN TIME- 2.0sec
SERUM CREATININE - 0.6 mg/dl
HIV - non reactive
Anti HCV antibodies -non reactive
USG
Bone marrow biopsy
Final Diagnosis : splenomegaly with pancytopenia
TREATMENT :-
•tab LIVOGEN - 150mg OD
•tab ULTRACET -500mg TID
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